… insights in the complex pathophysiology of glomerular diseases. Single-cell RNA sequencing
(scRNA-seq) and single-nucleus RNA-seq (snRNA-seq) are powerful new methods that …

… This was consistent with the findings of our previous bulk RNA sequencing data of sorted
GECs from the same animal model, 4 although there was only approximately 10% overlap in …

… those with autoimmune diseases, idiopathic glomerular diseases, and AKI. Clinicopathologic
diagnoses were diabetic kidney disease (n=6), hypertensive or vascular disease (n=13), or …

… utility in other glomerular diseases, we … bulk RNA-seq data of urine samples from another
multiethnic cohort of subjects with lupus nephritis and found that subjects with active disease (…

… We performed single-cell RNA sequencing analysis (… identifying rare cells related to the
disease by using the single-… diabetic kidney diseases by scRNA-seq of glomerular cells (19). Xi …

… disease (CKD) leads to upregulation of plasma Gal-3 expression in corresponding biopsy
findings and RNA sequencing … Gal-3 levels, estimated glomerular filtration rate (eGFR) and …

… RNA sequencing (RNA-Seq) accelerates the discovery of novel ncRNAs because RNA-Seq …
anti-glomerular basement membranous glomerulonephritis (anti-GBM GN) and nonimmune …

… RNA sequencing (RNA-seq). Application of these single-cell methods to glomerular diseases
… will also discuss how this approach could be applied to other primary glomerular diseases. …

… Third, the GEO dataset used in this study is derived from glomerular tissue, which may
mask cell-type-specific expression changes. Further studies are warranted to overcome the …

… Steffen Durinck for kindly providing the published glomerular disease data. This study was
supported by grants from KI/AZ Integrated Cardio Metabolic Center (JP and CB), Swedish …