Single-cell RNA sequencing of human kidney

J Liao, Z Yu, Y Chen, M Bao, C Zou, H Zhang, D Liu… - Scientific data, 2020 - nature.com
human kidney, we rapidly obtained a single-cell suspension of the kidney and conducted
single-cell RNA sequencing (… high-quality cells from the kidneys of three human donors. In this …

Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing

A Schumacher, MB Rookmaaker, JA Joles… - NPJ Regenerative …, 2021 - nature.com
human renal cell types, we discuss research that used single-cell RNA sequencing on developing
and adult human kidney … of the pre-single-cell RNA sequencing era. We find that these …

A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys

BB Lake, S Chen, M Hoshi, N Plongthongkum… - Nature …, 2019 - nature.com
RNA sequencing (snDrop-Seq) that we use to resolve thirty distinct cell populations in human
adult kidney. … nephron segments spanning two major kidney regions. We further delineate …

RNA sequencing identifies novel translational biomarkers of kidney fibrosis

FL Craciun, V Bijol, AK Ajay, P Rao… - Journal of the …, 2016 - journals.lww.com
… mouse model of progression to kidney fibrosis induced by folic … Using RNA sequencing
(RNA-seq) in the fibrotic kidneys, we … in animal models and humans with kidney fibrosis. We also …

[PDF][PDF] Dissecting the global dynamic molecular profiles of human fetal kidney development by single-cell RNA sequencing

P Wang, Y Chen, J Yong, Y Cui, R Wang, L Wen… - Cell reports, 2018 - cell.com
… key features of human fetal kidney development, we applied single-cell RNA sequencing
(… We classified the major cell types found in human fetal kidneys and defined their gene …

[HTML][HTML] The promise of single-cell RNA sequencing for kidney disease investigation

H Wu, BD Humphreys - Kidney international, 2017 - Elsevier
… as acute kidney injury and chronic kidney disease, … kidney is 1 expressed goal of the
NIDDK Kidney Precision Medicine Project 45 and will inform our understanding of healthy kidney

Fibrosis in pathology of heart and kidney: from deep RNA-sequencing to novel molecular targets

F Schreibing, TM Anslinger, R Kramann - Circulation Research, 2023 - Am Heart Assoc
… In this review, we briefly touch on the evolution of RNA-sequencing techniques and … of the
pathogenesis of heart and kidney fibrosis. Finally, we explain how RNA-seq and, in particular, …

Application of small RNA sequencing to identify microRNAs in acute kidney injury and fibrosis

KL Pellegrini, CV Gerlach, FL Craciun… - Toxicology and applied …, 2016 - Elsevier
… small RNA sequencing to profile miRNAs expressed during injury and fibrotic phases of kidney
… mouse models of kidney injury and fibrosis as well as in human kidney biopsy specimens …

Single-nucleus RNA sequencing identifies new classes of proximal tubular epithelial cells in kidney fibrosis

YA Lu, CT Liao, R Raybould, B Talabani… - Journal of the …, 2021 - journals.lww.com
… Single-nuclear RNA sequencing revealed phenotypes of … kidney function and to regeneration
versus organ fibrosis following injury. This study used single-nucleus RNA sequencing (…

[HTML][HTML] Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses

F Qi, S Qian, S Zhang, Z Zhang - Biochemical and biophysical research …, 2020 - Elsevier
… The kidneys are the part of urinary system. Most of the cells in kidney are proximal tubule
cells (Proximal Ts) (∼82%) (figs2). Besides, we annotated immune cells (∼8%), collecting duct …