… Messenger RNA (mRNA) vaccine technology has shown its power in preventing the … of
ARCoV in a nonhuman primate model. Two doses of ARCoV vaccination induced high level of …

… used to assess NAb induced by RNA vaccines. NAbs were first detected in the serum of
MRT5500-injected macaques at one week, mRNA-1273, ARCoV and LION/repRNA-CoV2S–…

… vaccines or treatments are available for human use. We evaluated the effects in nonhuman
primates of vaccine … The following immunogens were used: RNA replicon particles derived …

… Increasing SARS-CoV-2 specific IgG and NAb titers were observed from week three post-vaccination.
Viral RNA was detected in vaccinated animals early after infection, but viral …

… -2 RNA and subgenomic (sg) RNA in the nasal swabs of the animals throughout the study.
Interestingly, IN vaccination resulted in significantly lower levels of nasal viral RNA on dpc 1 …

… While this study only analyzed viral, not subgenomic, RNA, it seems highly unlikely that
gastrointestinal viral RNA could simply represent residual challenge virus. Thus, the higher-dose …

… vaccine against challenge in nonhuman primates (NHPs). When a single dose of the VSV-SARS2-EBOV
vaccine … in total SARS-CoV-2 RNA and subgenomic RNA (sgRNA) in the nasal …

… Additional timepoints post complete clearance of viral RNA from vaccinated … non-human
primate sera. We thank Battelle Memorial Institute for execution of the non-human primate …

… protection against ZEBOV in non-human primates provides a model for the treatment of
ZEBOV-induced haemorrhagic fever. These data show the potential of RNA interference as an …

… nonhuman primate species for evaluation of their vaccine and/or therapeutic candidates.
A number of Old World and New World monkey species are not endangered or threatened in …