[HTML][HTML] Protection of non-human primates against rabies with an adenovirus recombinant vaccine

ZQ Xiang, L Greenberg, HC Ertl, CE Rupprecht - Virology, 2014 - Elsevier
… New vaccine strategies are needed for human rabies prophylaxis. A single intramuscular …
a lethal rabies virus challenge infection in a non-human primate model. Taken together, these …

Immunization of non-human primates with DNA vaccines

MA Liu, W McClements, JB Ulmer, J Shiver, J Donnelly - Vaccine, 1997 - Elsevier
… The pre-clinical eSJicacy of DNA vaccines has been demonstrated in a number of animal …
in non-human primates. The studies described below demonstrate that DNA vaccines in …

[HTML][HTML] Distinct dynamics of mRNA LNPs in mice and nonhuman primates revealed by in vivo imaging

K Lemdani, R Marlin, C Mayet, V Perkov, Q Pascal… - npj Vaccines, 2024 - nature.com
nonhuman primate sera. These observations highlight the influence of the nature of the LNP
on mRNA vaccine … of RNA vaccines, which can be amplified by certain lipid formulations 37 . …

Immunogenicity and safety of a DNA prime/adenovirus boost vaccine against rhesus CEA in nonhuman primates

L Aurisicchio, C Mennuni, P Giannetti… - … journal of cancer, 2007 - Wiley Online Library
… as nonhuman primates. To verify the efficacy of genetic cancer vaccines in nonhuman
primates we … Colon samples from 2 different rhesus monkeys were used as RNA source for our …

A single dose respiratory recombinant adenovirus-based vaccine provides long-term protection for non-human primates from lethal Ebola infection

JH Choi, K Jonsson-Schmunk, X Qiu… - Molecular …, 2015 - ACS Publications
… sublingual (SL) adenovirus-based vaccine in non-human primates in two phases. In the …
RNA Mini Kit (Qiagen). Ebola virus RNA was detected by a qRT-PCR assay targeting the RNA

Immunization with RBD-P2 and N protects against SARS-CoV-2 in nonhuman primates

SH Hong, H Oh, YW Park, HW Kwak, EY Oh… - Science …, 2021 - science.org
… Here, we developed a previously unknown subunit vaccine … tested its efficacy in rodents
and nonhuman primates (NHPs). We … Viral RNA copy numbers from swab and tissue samples …

Nonhuman primates as models for the discovery and development of ebolavirus therapeutics

AC Shurtleff, TK Warren, S Bavari - Expert opinion on drug …, 2011 - Taylor & Francis
vaccines or therapeutics are currently licensed; however, several therapeutic agents have
shown promising efficacy in nonhuman primate … alter the efficiency of viral RNA replication and …

[HTML][HTML] Rapid protection of nonhuman primates against Marburg virus disease using a single low-dose VSV-based vaccine

KL O'Donnell, F Feldmann, B Kaza, CS Clancy… - …, 2023 - thelancet.com
… -MARV has previously been demonstrated in nonhuman primates. A dose of 1 × 10 7 … RNA
extract were run alongside dilutions of MARV standards with a known concentration of RNA

Establishment of a nonhuman primate model for development of vaccines and anti-viral drugs against COVID-19

Y ITOH - Translational and Regulatory Sciences, 2021 - jstage.jst.go.jp
… human ACE2 transgenic mice when evaluating the efficacy of vaccines and drugs. … RNA
was detected in swab samples on day 1. The amount gradually decreased; however viral RNA

[HTML][HTML] A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge

C Woolsey, RW Cross, KN Agans… - PLoS neglected …, 2022 - journals.plos.org
… transcriptomics on whole blood RNA from MARV-exposed vaccinated macaques. Spatial …
analyses (PCA) indicated RNA samples clustered independently of time of vaccination (group), …