[HTML][HTML] Circular RNA vaccines against SARS-CoV-2 and emerging variants

L Qu, Z Yi, Y Shen, L Lin, F Chen, Y Xu, Z Wu, H Tang… - Cell, 2022 - cell.com
vaccines that offer more effective and broad-spectrum protection. Here, we report a circular
RNA (circRNA) vaccine … , providing robust protection against SARS-CoV-2 in both mice and …

[HTML][HTML] Vaccines' new era-RNA vaccine

W Zhou, L Jiang, S Liao, F Wu, G Yang, L Hou, L Liu… - Viruses, 2023 - mdpi.com
… -19 pandemic caused by the SARS-CoV-2 virus that emerged in 2019 has highlighted the
potential of RNA vaccines. These vaccines possess several advantages, such as high efficacy…

[HTML][HTML] SARS-CoV-2 vaccines in development

F Krammer - Nature, 2020 - nature.com
… , a vaccine is urgently needed. Here I review the development of vaccines against SARS-CoV-2. …
RNA vaccines have shown great promise in recent years and many of them are in …

[HTML][HTML] RNA vaccines: a suitable platform for tackling emerging pandemics?

JB Sandbrink, RJ Shattock - Frontiers in immunology, 2020 - frontiersin.org
… of an RNA-based delivery mechanism promises fast vaccineRNA vaccines are safe in
theory and have shown acceptable … Immunogenicity of SARS-CoV-2 mRNA vaccines in phase 1 …

[HTML][HTML] Immunogenicity of SARS-CoV-2 messenger RNA vaccines in patients with cancer

A Addeo, PK Shah, N Bordry, RD Hudson, B Albracht… - Cancer cell, 2021 - cell.com
… We examined antibody response after the first and second doses of vaccines in the subset
of patients with prior SARS-CoV-2 infection who were excluded from the overall vaccine

Evaluation of seropositivity following BNT162b2 messenger RNA vaccination for SARS-CoV-2 in patients undergoing treatment for cancer

A Massarweh, N Eliakim-Raz, A Stemmer… - JAMA …, 2021 - jamanetwork.com
… are at high risk of COVID-19 following SARS-CoV-2 infection; however, their ability to
produce an adequate antibody response to messenger RNA SARS-CoV-2 vaccines is unclear. …

[HTML][HTML] Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults

MJ Mulligan, KE Lyke, N Kitchin, J Absalon, A Gurtman… - Nature, 2020 - nature.com
… RBD of the spike protein of SARS-CoV-2, a key target of virus-… The vaccine RNA is formulated
in lipid nanoparticles for more… of several RNA-based SARS-CoV-2 vaccine candidates 18 …

Safety and immunogenicity of anti–SARS-CoV-2 messenger RNA vaccines in recipients of solid organ transplants

O Marion, A Del Bello, F Abravanel… - Annals of internal …, 2021 - acpjournals.org
… Society of Transplantation, anti–SARS-CoV-2 spike protein antibodies were monitored
before and after vaccination. We used the SARS-CoV-2 total antibodies enzyme-linked …

An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

JH Erasmus, AP Khandhar, MA O'Connor… - Science translational …, 2020 - science.org
… studies of SARS-CoV-2 S–targeted DNA and live viral vector vaccines tested in nonhuman
primates (53, 58). In addition, the ability of our repRNA vaccine to induce anti–SARS-CoV-2 S…

SARS-CoV2 variant-specific replicating RNA vaccines protect from disease following challenge with heterologous variants of concern

DW Hawman, K Meade-White, J Archer, SS Leventhal… - Elife, 2022 - elifesciences.org
vaccines that can protect against multiple VoC. In this report, we evaluated an alphavirus- …
replicating RNA vaccine expressing Spike proteins from the original SARS- CoV- 2 Alpha …