The fitness effects of synonymous mutations in DNA and RNA viruses

JM Cuevas, P Domingo-Calap… - Molecular biology and …, 2012 - academic.oup.com
… We conclude that, although selection is mainly exerted at the protein level both in ssRNA
and ssDNA viruses, RNA-level selection plays also a significant role in ssRNA viruses. The …

Experimental evolution of plant RNA viruses

SF Elena, P Agudelo-Romero, P Carrasco… - Heredity, 2008 - nature.com
… In addition, RNA viruses also present large selection coefficients, antagonistic epistasis, …
and that of maintaining mutational load at as low a level as possible. It has been postulated that, …

Is group selection a factor modulating the virulence of RNA viruses?

R Miralles, A Moya, SF Elena - Genetics Research, 1997 - cambridge.org
… have evolved by selection between different groups. … selection acts on the lower levels of
the hierarchy. The problem with this view, however, is to define what is meant by the lower level

… of synonymous codon usage bias patterns in DNA and RNA virus genomes: quantifying the relative importance of mutational pressure and natural selection

Y Chen - BioMed research international, 2013 - Wiley Online Library
… by natural selection for DNA and RNA viruses, respectively, in … selection on influencing
codon usage patterns of viruses is … DNA and RNA viruses, being positive for DNA viruses while …

Emergence and selection of RNA virus variants: memory and extinction

E Domingo, CM Ruiz-Jarabo, S Sierra, A Arias… - Virus research, 2001 - Elsevier
… secure an adequate fidelity level during replication of complex cellular DNA. The biology
of RNA viruses is extremely influenced by high mutation rates. Viral populations consist of …

New observations on antigenic diversification of RNA viruses. Antigenic variation is not dependent on immune selection

E Domingo, J Diez, MA Martinez… - Journal of General …, 1993 - microbiologyresearch.org
… structure of RNA viruses. Results from studies with field isolates of viruses and analysis of
virus … will be kept at low levels (or will be eliminated) by negative selection. As a consequence, …

Evolutionary potential of an RNA virus

EV Makeyev, DH Bamford - Journal of virology, 2004 - Am Soc Microbiol
… marker introduced into an RNA virus genome is employed as a selection target. Bacteriophage
viral adaptation on the molecular level has several advantages as follows. (i) Selection is …

RNA viruses: a case study of the biology of emerging infectious diseases

ME J. Woolhouse, K Adair, L Brierley - Microbiology Spectrum, 2013 - Am Soc Microbiol
… species of human RNA virus reported every year just to maintain the level of diversity that …
, please select Medlars format which will download as a .txt file. Simply select your manager …

Are RNA viruses adapting or merely changing?

M Sala, S Wain-Hobson - Journal of molecular evolution, 2000 - Springer
RNA viruses and retroviruses fix substitutions approximately … an inevitable drift under
purifying selection, the majority of … For a large and diverse selection of viruses it is shown here …

Collective action in an RNA virus

SP Brown - Journal of Evolutionary Biology, 2001 - academic.oup.com
… Furthermore, the collective action model is used to motivate discussion on the evolutionary
ecology of viruses, with a focus on the ‘levels of selection’ debate and the evolution of …