I Weissberg, L Wood, L Kamintsky, O Vazquez… - Neurobiology of …, 2015 - Elsevier
… similar epileptogenic effects that are prevented by the specific inhibition of the TGF-β\ALK5 pathway. Our findings validate the role of TGF-β in PIE, supporting the epileptogenicrole of …
JA Gorter, E Aronica, EA Van Vliet - Epilepsy currents, 2019 - journals.sagepub.com
… Research into the role of the blood–brainbarrier (BBB) in epilepsy … epileptogenicbrain tissue. At the same time it has become increasingly clear that (neuro)inflammation may play a role …
M Kaya, AJ Becker, C Gürses - Epilepsia, 2012 - Wiley Online Library
… This article presents the results of two separate studies on the involvement of blood–brain barrier (BBB) in epilepsy. The first focuses on the effects of antiepileptic drugs in animal …
H Breuer, M Meier, S Schneefeld… - Journal of Cerebral …, 2017 - journals.sagepub.com
… Our findings will help to further evaluate the role of BBB impairment in epileptogenesis and provide a potential method to optimize timing of BBB protective treatment approaches. …
D Janigro - Epilepsy Currents, 2007 - journals.sagepub.com
… In addition to acute seizures, there is new evidence that inflammation may also play a role in epileptogenesis, although no antiinflammatory compounds have yet been shown to be …
… acute OP intoxication causes BBB impairment and its role in the … blood-brainbarrier (BBB) dysfunction and epileptogenesis; … relationships between BBB dysfunction and epilepsy may …
K Itoh, Y Ishihara, R Komori, H Nochi, R Taniguchi… - Brain Research, 2016 - Elsevier
… These results suggested that the relationship between microglia activation and neuronal cell death in the acute phase of epileptogenesis might play an important role in the …
W Löscher - … and Pathology of the Blood-Brain Barrier, 2020 - Springer
… –brainbarrier (BBB) is a dynamic and complex barrier essential for the normal function of … This led to the concept that epileptogenicbrain insults and seizures induce a non-specific “…
M Bankstahl, H Breuer, I Leiter, M Märkel, P Bascuñana… - Eneuro, 2018 - eneuro.org
… subsequent impairment of the NVU, our data support the necessity of a prompt BBB-restoring treatment as one component of rational therapeutic intervention to prevent epileptogenesis …