Epilepsy and brain inflammation

A Vezzani, E Aronica, A Mazarati, QJ Pittman - Experimental neurology, 2013 - Elsevier
… , its involvement in epileptogenesis is still hypothetical, although long-term effect of brain
In favor of such pro-epileptogenic role there is evidence that CNS injuries such as trauma, …

Links between immune cells from the periphery and the brain in the pathogenesis of epilepsy: a narrative review

G Yamanaka, S Morichi, T Takamatsu… - International journal of …, 2021 - mdpi.com
… detected in epileptogenic areas of the human brain, even in … after the disruption of the
blood–brain barrier (BBB), which is … explore the current literature on the role of the link between …

Animal models of acquired epilepsy: insights into mechanisms of human epileptogenesis

AJ Becker - Neuropathology and applied neurobiology, 2018 - Wiley Online Library
brain barrier dysfunction as well as innate and adaptive immunity-mediated damage play
major roles… interfering with epileptogenic mechanisms. Well-controlled subsequent analyses of …

Inflammation in epileptogenesis after traumatic brain injury

KM Webster, M Sun, P Crack, TJ O'Brien… - Journal of …, 2017 - Springer
… published evidence regarding the role of inflammation in the … epileptogenesis. Lastly,
potential mechanisms underlying age-specific vulnerability to hyperexcitability and epileptogenesis

Blood–brain barrier disruption in post-traumatic epilepsy

O Tomkins, I Shelef, I Kaizerman, A Eliushin… - Journal of Neurology …, 2008 - jnnp.bmj.com
brain barrier (BBB) plays a critical role in the pathogenesis of post-traumatic epilepsy (PTE). …
Recent animal experiments show that opening the blood–brain barrier (BBB) leads to …

Perivascular Inflammation and Extracellular Matrix Alterations in Blood-Brain Barrier Dysfunction and Epilepsy

DWM Broekaart, A Korotkov, JA Gorter… - … and Epilepsy: New …, 2021 - Springer
role in epileptogenesis. In this chapter we aim to give an overview of the processes involved
in BBB dysfunction and epileptogenesis and … We will focus on modulators of BBB function

Neurovascular unit dysfunction as a mechanism of seizures and epilepsy during aging

EA van Vliet, N Marchi - Epilepsia, 2022 - Wiley Online Library
… supporting the involvement of NVU dysfunction, within a pro-… (NVU) dysfunction, including
increased blood-brain barrier (BBB) … BBB dysfunction, brain inflammation, and epileptogenesis

Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood–brain barrier

D Janigro - Epilepsia, 2012 - Wiley Online Library
brain barrier (BBB) and the ‘‘neurovascular unit.’’ Therefore, the pursuit of mechanisms of
seizure generation and epileptogenesis now includes investigations of cerebral … proposed role

Blood‐brain barrier breakdown following traumatic brain injury: a possible role in posttraumatic epilepsy

O Tomkins, A Feintuch, M Benifla… - Cardiovascular …, 2011 - Wiley Online Library
… serum protein, albumin, may underlie astrocytic activation and dysfunction, further leading
to neuronal hypersynchrony (ie, epileptogenesis) and accumulated neuronal loss [13, 14]. …

[HTML][HTML] Cytosolic phospholipase A2 is a key regulator of blood–brain barrier function in epilepsy

AMS Hartz, RG Rempe, ELB Soldner, A Pekcec… - The FASEB …, 2019 - ncbi.nlm.nih.gov
… Blood–brain barrier dysfunction in epilepsy contributes to seizures and resistance to …
brain glutamate levels, leading to barrier dysfunction. One component of barrier dysfunction is …