SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
… the role of cytokine storm associated with SARS-CoV-2 … cytokine profiles in patients infected
with SARS-CoV-2 and their relationship to the severity of the disease. A total of 14 cytokines

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARSCoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
cytokines in SARS-CoV-2 infection and discuss their potential roles in triggering or regulating
cytokine … So far, there is rarely effective therapeutic strategy for patients with cytokine storm …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
… with severe acute respiratory syndrome coronavirus 2, leading to clinical … to as cytokine
storm in its severest form has been marked by elevation of IL-6, IL-10, TNF-α, and other cytokines

Exploring the role of immune system and inflammatory cytokines in SARS-CoV-2 induced lung disease: a narrative review

C Tirelli, M De Amici, C Albrici, S Mira, G Nalesso, B Re… - Biology, 2023 - mdpi.com
SARS-CoV-2 infection may induce an over activation of the immune system … cytokines,
leading to a “cytokine storm”, a recognized pathogenetic mechanism in the genesis of SARS-CoV-…

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… effectively suppress cytokine storm … , SARS-CoV-2 and the mechanisms by which cytokine
storm is induced by the virus will be introduced in detail, including the ways in which cytokines

… of elevated levels of pro‐inflammatory cytokines in SARSCoV‐infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS

L He, Y Ding, Q Zhang, X Che, Y He… - The Journal of …, 2006 - Wiley Online Library
SARS) and that the SARS coronavirus (SARS-CoV) nucleoprotein is detectable in the lungs,
and other organs and tissues, in these patients. In the present study, immunohistochemistry …

Role of SARS-CoV-2-induced cytokines and growth factors in coagulopathy and thromboembolism

F Ahmad, M Kannan, AW Ansari - Cytokine & Growth Factor Reviews, 2022 - Elsevier
… Severe SARS-CoV-2 infection induces the cytokine storm and is often associated with …
effect of SARS-CoV-2 infection on the coagulation system is largely undefined. SARS-CoV-2 –…

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
cytokine responses caused by these viruses. Our curation indicates that the cytokine response
induced by SARS-CoV-2 … , as SARS-CoV-2 does not always induce specific cytokines like …

Interferon and cytokine responses to SARS-coronavirus infection

V Thiel, F Weber - Cytokine & growth factor reviews, 2008 - Elsevier
… i) massive immune cell infiltrations found in the lungs of SARS victims, and (ii) the dysregulation
… of SARS-CoV and related Coronaviridae members with the type I interferon and cytokine

Cytokine storm syndrome in SARS-CoV-2 infections: a functional role of mast cells

B Hafezi, L Chan, JP Knapp, N Karimi, K Alizadeh… - Cells, 2021 - mdpi.com
… a cytokine response by mast cells may initiate inappropriate antiviral immune responses and
cause the development of cytokine … Recognition of the cytokine storm is crucial for proper …