2 天前 - … -sensing ion channel 3 (ASIC3) in sensory neurons may have a role in this condition.
… of IMQ, suggesting that nociceptor-expressed ASIC3 has a role in psoriatic inflammation. …

2 天前 - … TIM-1 and -3 play distinct roles in autoimmunity, with TIM-1 acting as a costimulatory
… We investigated the therapeutic potential of anti-TIM-1 (RMT1-10) and anti-TIM-3 (RMT3-23…

3 天前 - Complement factor H-related protein (CFHR) plays an important role in regulating
complement activation and defensive responses. The function of CFHR2 (complement factor …

3 天前 - Aim. To clarify the role of advanced glycation end products (AGEs) and inflammation
in the development of vascular calcification and cardiovascular complications at different …

4 天前 - … In GPP, the innate immune system seems to play a more significant role, with the
interleukin (IL)-36 pathway being fundamentally involved. Spesolimab and imsidolimab, two …

4 天前 - … investigated the role of β-mangostin on microglia in the glioma microenvironment
and evaluated the efficacy of β-mangostin combined with anti-PD-1 antibody (αPD-1) in …

4 天前 - … Interleukin-1 receptor-associated kinase 4 (IRAK4) is a … role in Toll-like receptor
(TLR) and Interleukin-1 receptor (IL-1R) signaling pathways. Due to IRAK4’s significant role in …

4 天前 - … Cryopyrin-Associated Periodic Syndromes (CAPS) encompasses a spectrum of
Interleukin-1 (IL-1) driven systemic diseases with dramatic individual and societal burden. The …

5 天前 - … to elevated expressions of the collagen degradation factors matrix metalloproteinase
(MMP)‐1 and MMP‐2 and inflammatory factors such as interleukin (IL)‐1β and IL‐6. …

5 天前 - … Recent reports indicate that NOD-like receptor protein 3 (NLRP3)-mediated
pyroptosis plays a significant role in the calcification of vascular smooth muscle cells (VSMCs), …