… involvement of interleukin-1 in the … a role for interleukin-1 in acute neurodegeneration —
for example, stroke and brain trauma — and provides a rationale for targeting the interleukin-1 …

… Aqueous extracts prepared from pulmonary granuloma lesions induced in sensitized mice
by antigen-coated beads contained high levels of interleukin 1 (IL 1) and migration inhibition …

Interleukin 1 receptor (IL-1R)-associated kinase-4 (IRAK-4) is required for various responses
induced by IL-1R and Toll-like receptor signals. However, the molecular mechanism of …

… This chapter will consider in detail the characteristics and functional role of the Ig domain
receptor subfamily in the regulation of host defense and their possible role in pathology. …

… Interleukin-1 (IL-1)-1) is a pluripotent immunomodulatory cytokine that has an initiating role
in cellular and humoral immunity in the periphery. Il-1 is overexpressed in Alzheimer brain, …

… identify this second cofactor as the previously described monokine interleukin 1 (IL-1). … or
IL-1 on activated mouse B cells has yet been obtained. This report establishes a role for IL-1 in …

… ‐IL‐1 (α + β), but not with anti‐TNF, resulted in normal PG synthesis, confirming the key role
played by IL‐1 in the inhibition of PG synthesis. Treatment of AIA with anti‐IL‐1 did not affect …

… We propose a similar requirement for IL-1–dependent NO production in our mouse model
of silicosis as in autoimmune diabetes and suggest a role for macrophage apoptosis in the …

… The polypeptide cytokine interleukin-1 (IL-1) affects nearly every tissue and organ system.
IL-1 is the prototype of the pro-inflammatory cytokines in that it induces the expression of a …

Isolating rats immediately after conditioning impairs contextual but not auditory-cue fear
conditioning. The reported experiments examine the involvement of brain interleukin-1β (IL-1β) …