Efficacy and safety of remdesivir in COVID-19 caused by SARS-CoV-2: a systematic review and meta-analysis

S Singh, D Khera, A Chugh, PS Khera, VK Chugh - BMJ open, 2021 - bmjopen.bmj.com
… –risk ratio of remdesivir. Current review was planned to assess the mortality and clinical
benefit in addition to safety of remdesivir in the treatment of COVID-19 caused by SARS-CoV-2. …

Evaluation of the safety profile and therapeutic efficacy of remdesivir in children with SARS-CoV-2 infection–a single-center, retrospective, cohort study

K Kautsch, J Wiśniowska… - European Journal of …, 2024 - Springer
… In conclusion, remdesivir is a safe form of treatment for COVID-19, with a small number of
side effects that in the vast majority of cases do not require discontinuation of treatment; yet, the …

Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes

SW Choi, JS Shin, SJ Park, E Jung, YG Park, J Lee… - Antiviral research, 2020 - Elsevier
… In summary, we generated hPSC-CMs to evaluate anti-SARS-CoV-2 activity as well as the
safety of remdesivir in physiologically and disease-relevant human cells. This study provides …

[HTML][HTML] Therapeutic dilemmas in addressing SARS-CoV-2 infection: Favipiravir versus Remdesivir

PA Negru, AF Radu, CM Vesa, T Behl… - Biomedicine & …, 2022 - Elsevier
safety profiles have made favipiravir (FVP) and remdesivir (RDV) promising therapeutic options
for use against severe acute respiratory syndrome coronavirus 2 (SARS-CoVSARS-CoV-…

Efficacy and safety of remdesivir over two waves of the SARS-CoV-2 pandemic

M Poliseno, C Gallo, DC Cibelli, GA Minafra… - Antibiotics, 2021 - mdpi.com
Safety and Cardiac Rhythm Abnormalities There were 133 patients included in the study of
Remdesivir heart safety, … of our work was to describe the safety of Remdesivir in terms of drug-…

[HTML][HTML] Safety profile of the antiviral drug remdesivir: An update

Q Fan, B Zhang, J Ma, S Zhang - Biomedicine & Pharmacotherapy, 2020 - ncbi.nlm.nih.gov
… respiratory syndrome coronavirus 2 (SARS-CoV-2), has posed a serious threat to the global
public health. There is an urgent demand for safe and effective therapeutics. Remdesivir, a …

Remdesivir use in pediatric patients for SARS-CoV-2 treatment: single academic center study

AM Samuel, LL Hacker, J Zebracki… - The Pediatric …, 2023 - journals.lww.com
… from the CARAVAN study, this review allows more information to be gathered regarding
the safety and efficacy of a shorter duration of remdesivir therapy in pediatric patients with …

Arguments in favour of remdesivir for treating SARS-CoV-2 infections

WC Ko, JM Rolain, NY Lee, PL Chen, CT Huang… - International journal of …, 2020 - Elsevier
… of SARS-CoV infection, potent antiviral activity against SARS-CoV-2, acceptable safety profile
of parenteral remdesivir … virus disease, the clinical use of remdesivir in the cases of COVID-…

The safety, tolerability and mortality reduction efficacy of remdesivir; based on randomized clinical trials, observational and case studies reported safety outcomes: an …

C Santenna, K Vidyasagar… - … in Drug Safety, 2021 - journals.sagepub.com
… We have performed a systematic search in the PubMed, Google Scholar and Cochrane
Library using specific keywords such as ‘COVID-19’ OR ‘SARS CoV-2’ AND ‘Remdesivir’. The …

Using integrated computational approaches to identify safe and rapid treatment for SARS-CoV-2

K Al-Khafaji, D Al-Duhaidahawi… - Journal of Biomolecular …, 2021 - Taylor & Francis
… One of the more noteworthy findings in this study is that MD simulation analysis that saquinavir,
ritonavir, and remdesivir can form stable interaction inside the binding site of SARS-CoV-…