… for COVID-19. Here, we focus our attention on ACE2, a primary receptor of SARS-CoV-2. We … to be employed by SARS-CoV-2 for cell entry. Particular attention will be given to how the …
L Samavati, BD Uhal - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
… The virus gains entrance into its host cell via the ACE2receptor. How the known epidemiological and clinical manifestation of SARS-CoV-2 … of the ACE2receptor due to receptorvirus …
… involved in the SARS-CoV-2 S-protein interaction. Overall, we found human ACE2receptor … and the ACE2 PD showed even more reduced variation (Wilcoxon p-value = 0.0656, n = 65, …
H Zhang, MR Rostami, PL Leopold… - American journal of …, 2020 - atsjournals.org
… From this data, we conclude that the ACE2receptor for SARS-CoV-2 is distributed throughout the lung epithelial surface and that the site of infection would be dictated by the size of the …
Y Li, W Zhou, L Yang, R You - Pharmacological research, 2020 - Elsevier
… ACE2 was identified as the receptor of severe acute respiratory syndrome coronavirus2 (SARS-CoV-2), the coronavirus … evidence that ACE2 is the receptor for SARS-CoV-2. Results in …
P Verdecchia, C Cavallini, A Spanevello… - European journal of …, 2020 - Elsevier
… Angiotensin converting enzyme-2 (ACE2) receptors mediate the entry into the cell of three strains of coronavirus: SARS-CoV, NL63 and SARS-CoV-2. ACE2receptors are ubiquitous …
… of the polymorphisms on receptor recognition by the SARS-CoV-2 RBD and to confirm … ACE2 variants using the recently published cryo-EM and crystal structures of ACE2/SARS-CoV-2 …
… the ACE2-binding affinity among SARS-CoV-2, SARS-CoV … of the SARS-CoV-2 RBM that result in tight ACE2 binding. They … the structural basis of ACE2 recognition by SARS-CoV-2, we …
… glycoproteins (Env) with receptors [9], we propose a possible mechanism of the ACE2 function as a receptor for the SARSvirus. The analysis of the ACE2 model could also help in the …