In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies

D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer… - Cell, 2021 - cell.com
SARS-CoV-2-neutralizing antibodies (NAbs) protect against COVID-19. A concern regarding
SARS-CoV-2 antibodies is whether they mediate disease enhancement. Here, we isolated …

[HTML][HTML] SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies

MG Cox, TP Peacock, WT Harvey, J Hughes… - Nature Reviews …, 2023 - nature.com
… Monoclonal antibodies (mAbs) offer a treatment option for individuals with severe COVID-19
to mAbs by SARS-CoV-2, we reviewed the available in vitro neutralization data for mAbs …

In vitro evaluation of therapeutic antibodies against a SARS-CoV-2 Omicron B. 1.1. 529 isolate

F Touret, C Baronti, HS Bouzidi, X de Lamballerie - Scientific Reports, 2022 - nature.com
… of COVID-19 therapeutic antibodies against a clinical strain of the Omicron variant. The panel
consists of therapeutic antibodies that … Within this panel, all antibodies retained neutralizing …

An in vitro microneutralization assay for SARSCoV2 serology and drug screening

F Amanat, KM White, L Miorin… - Current protocols in …, 2020 - Wiley Online Library
… used to assess the extent to which antibodies are able to neutralize SARS-CoV-2 in vitro.
Serum or plasma samples from any species, as well as monoclonal antibodies (mAbs), can be …

The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates

D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer… - BioRxiv, 2021 - biorxiv.org
… potent in vitro neutralizing RBD and NTD antibodies as well as in vitro infection-enhancing
RBD and NTD antibodies from individuals infected with SARS-CoV-1 or SARS-CoV-2. …

501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in vitro

H Liu, P Wei, Q Zhang, Z Chen, K Aviszus, W Downing… - MAbs, 2021 - Taylor & Francis
antibody may be needed to treat COVID-19 patients infected with the United Kingdom variant
compared to patients with wildtype virus… , therapeutic antibodies to treat COVID-19 patients …

[HTML][HTML] SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma

E Andreano, G Piccini, D Licastro, L Casalino… - BioRxiv, 2020 - ncbi.nlm.nih.gov
… Our data also confirm that the SARS-CoV-2 neutralizing antibodies acquired during infection
target almost entirely the NTD and the RBD. In the RBD, the possibility to escape is limited …

Testing for SARS-CoV-2 (COVID-19): a systematic review and clinical guide to molecular and serological in-vitro diagnostic assays

A La Marca, M Capuzzo, T Paglia, L Roli… - Reproductive …, 2020 - Elsevier
… For the main objective of this review, all original studies reporting on the sensitivity and/or
specificity of antibodies against SARS-CoV-2 were included in the analysis. More than 20,000 …

Rapid in vitro assays for screening neutralizing antibodies and antivirals against SARS-CoV-2

JG Park, FS Oladunni, K Chiem, C Ye… - Journal of Virological …, 2021 - Elsevier
antibodies with neutralizing activity against SARS-CoV-2. … for SARS-CoV-2 infection and
associated COVID-19 disease. … to reduce SARS-CoV-2 infection and a handful of monoclonal …

In vitro activity of therapeutic antibodies against SARS-CoV-2 Omicron BA. 1, BA. 2 and BA. 5

F Touret, C Baronti, B Pastorino, PMS Villarroel… - Scientific Reports, 2022 - nature.com
… of activity of therapeutic antibodies currently licensed in the … BA.2 and BA.5 variants, we
compared the neutralising power of monoclonal antibodies against the Omicron BA.1, BA.2 and …