Sensitivity of infectious SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants to neutralizing antibodies

D Planas, T Bruel, L Grzelak, F Guivel-Benhassine… - Nature medicine, 2021 - nature.com
… syndrome coronavirus 2 (SARS-CoV-2) B.1.1.7 and B.1.351B.1.1.7 and B.1.351
strains from acutely infected individuals. We examined sensitivity of the two variants to SARS-CoV-2

[HTML][HTML] Antibody resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7

…, L Liu, S Iketani, Y Luo, Y Guo, M Wang, J Yu, B Zhang… - Nature, 2021 - nature.com
… or sera from individuals who have been vaccinated against SARS-CoV-2. The B.1.351 variant
is … Moreover, compared to wild-type SARS-CoV-2, B.1.351 is markedly more resistant to …

[PDF][PDF] Infection-and vaccine-induced antibody binding and neutralization of the B. 1.351 SARS-CoV-2 variant

…, G Michael, H Abdullahi, N Beydoun, B Panganiban… - Cell host & …, 2021 - cell.com
… RBD, sera from infected (acute and convalescent) and Moderna (mRNA-1273)-vaccinated
individuals were still able to neutralize the SARSCoV-2 B.1.351 variant, suggesting that …

[PDF][PDF] SARS-CoV-2 variants B. 1.351 and P. 1 escape from neutralizing antibodies

…, MS Winkler, S Schulz, HM Jäck, B Jahrsdörfer… - Cell, 2021 - cell.com
… The present study demonstrates that S proteins of SARS-CoV-2 WT, B.1.1.7, B.1.351, and
P.1 mediate cell-cell and virus-cell fusion with roughly comparable efficiency and entry kinetics…

[HTML][HTML] Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera

…, HME Duyvesteyn, A Tuekprakhon, R Nutalai, B Wang… - Cell, 2021 - cell.com
… for B.1.1.7 and B.1.351, is causing considerable concern. Here, we examine
neutralization of a B.1.351 viral isolate and compare this to neutralization of Victoria (SARS-CoV-2/human/…

Neutralising antibody activity against SARS-CoV-2 VOCs B. 1.617. 2 and B. 1.351 by BNT162b2 vaccination

…, S Gamblin, M Howell, G Kassiotis, V Libri, B Williams… - The Lancet, 2021 - thelancet.com
… -type, D614G, and B.1.1.7 remained within the quantitative range of our assay (IC 50 >40),
two participants' NAbTs against VOCs B.1.617.2 and B.1.351 dropped below 40 on their later …

[HTML][HTML] Detection of B. 1.351 SARS-CoV-2 variant strain—Zambia, december 2020

M Mwenda - MMWR. Morbidity and mortality weekly report, 2021 - cdc.gov
… displaced the majority of other SARS-CoV-2 lineages circulating in that country (2). As of …
with the B.1.351 variant. In Zambia, the average number of daily confirmed COVID-19 cases …

Protective efficacy of Ad26. COV2. S against SARS-CoV-2 B. 1.351 in macaques

J Yu, LH Tostanoski, NB Mercado, K McMahan, J Liu… - Nature, 2021 - nature.com
… We assessed vaccine-induced antibody responses against the SARS-CoV-2 WA1/2020
strain as well as against B.1.351. Using a luciferase-based pseudovirus neutralizing antibody …

[HTML][HTML] The SARS-CoV-2 B. 1.351 lineage (VOC β) is outgrowing the B. 1.1. 7 lineage (VOC α) in some French regions in April 2021

B Roquebert, S Trombert-Paolantoni… - …, 2021 - eurosurveillance.org
… validate our assumption that the transmission advantage belongs to B.1.351, to P.1, or to
both… be the B.1.351 lineage causes infections that have a shorter generation interval than the B.…

SARS-CoV-2 B. 1.1. 7 (alpha) and B. 1.351 (beta) variants induce pathogenic patterns in K18-hACE2 transgenic mice distinct from early strains

P Radvak, HJ Kwon, M Kosikova… - Nature …, 2021 - nature.com
B.1.1.7 and B.1.351 are 100-fold more lethal than the original SARS-CoV-2 bearing 614D. …
Our study demonstrates that B.1.1.7 and B.1.351 variants are more lethal than early SARS-…