… the total binding energy between ACE2 and SARS-CoV-2 is higher than in the case of
SARS-CoV, because of enhanced electrostatic interactions induced by the SARS-CoV-2 mutations…

… ’ proteolytic cleavage site, S810–S816), we hypothesized that SARS-CoV-2 may also interact
with host cell surface GAGs through its SGPs to invade host cell (Fig. 1, S2, and S3). The …

… In conclusion, we investigated the interaction established between the SARS-CoV-2 S …
binding mechanism between the S1 subunit and the ACE2 receptor. By comparing the binding of …

… shown that the SARS-CoV-2 S1 RBD binds to a … interactions of SARS-CoV-2 S1 RBD to
different amyloid forming proteins including Aβ, α-synuclein, tau, prions, and TAR DNA binding …

… binding and affinity difference between SARS-CoV-2 and SARS-CoV, we focus on specific
amino acid interactions in the three key binding contact regions (Fig. 1A). Although many …

… among RBD-binding human NAbs isolated from COVID-19-convalescent individuals 5 , we
… favourable ACE2 binding to the SARS-CoV-2 RBD 42 . Analysis of interactions by C144, …

… -host cells fusion and hence the infectivity of the virus [5,[12], [… SARS-CoV2 can alter the
binding of the virus to ACE2. We focus on the role of the electrostatic interactions on the binding …

… We have observed different degrees of binding interactions between spike protein and its
receptor (ACE2) from human and two of the most suspected zoonotic hosts/reservoirs (Figure 3…

… In this work, we utilize comprehensive approaches to study the SARS-CoV-2-ACE2
interactions from several perspectives such as the electrostatic surfaces, electric field lines and …

… Global Interactions between RBD and ACE2. To discriminate between the binding of the
SARS-CoV and SARS-CoV-2 RBDs to ACE2, we ran two 2-μs simulations, starting each from …