Cell entry mechanisms of SARS-CoV-2

J Shang, Y Wan, C Luo, G Ye, Q Geng… - Proceedings of the …, 2020 - National Acad Sciences
… to the immune evasion, cell infectivity, and wide spread of the virus. This study also …
cell entry of SARS-CoV-2. Finally, by highlighting the potency and the evasiveness of SARS-CoV-2, …

Cell entry by SARS-CoV-2

R Peng, LA Wu, Q Wang, J Qi, GF Gao - Trends in biochemical sciences, 2021 - cell.com
… syndrome virus 2 (SARS-CoV-2) invades host cells by … mediates fusion between viral and
cellular membranes. The host … the molecular events during SARS-CoV-2 entry which will …

[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - … reviews Molecular cell …, 2022 - nature.com
… converting enzyme 2 (ACE2), and subsequent membrane fusion. This Review provides the
structural and cellular foundations for understanding the multistep SARS-CoV-2 entry process…

The structural basis of accelerated host cell entry by SARSCoV2

M Seyran, K Takayama, VN Uversky… - The FEBS …, 2021 - Wiley Online Library
… rafts for binding, cell entry, assembly, and exit [[38]], and SARS-CoV cell entry through
the lipid rafts was detected on Vero cells [[39]]. Lipid raft-dependent structural model of virus-host …

ACE2: the major cell entry receptor for SARS-CoV-2

F Scialo, A Daniele, F Amato, L Pastore, MG Matera… - Lung, 2020 - Springer
… related coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2, respectively [2]. Their …
ACE)2 that is used by SARS-CoV-2 to gain entry into human cells [3]. There are two forms of …

SARS-CoV-2 spreads through cell-to-cell transmission

C Zeng, JP Evans, T King, YM Zheng… - Proceedings of the …, 2022 - National Acad Sciences
SARS-CoV-2 entry into host cells. We evaluated whether the spike protein of SARS-CoV-2
is critical for viral spread through cellcell … In order to compare the efficiency of cell-to-cell vs. …

[HTML][HTML] SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor

M Hoffmann, H Kleine-Weber, S Schroeder, N Krüger… - cell, 2020 - cell.com
… which cellular factors are used by SARS-CoV-2 for entry … that SARS-CoV-2 uses the
SARS-CoV receptor ACE2 for entry … A TMPRSS2 inhibitor approved for clinical use blocked entry

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

M Letko, A Marzi, V Munster - Nature microbiology, 2020 - nature.com
… lineage B viruses to enter human cells through an unknown receptor. We … entry into
human cells, and confirm that human ACE2 is the receptor for the recently emerging SARS-CoV-2

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

L Cantuti-Castelvetri, R Ojha, LD Pedro, M Djannatian… - Science, 2020 - science.org
… Having obtained evidence for a role of NRP1 in cell entry of SARS-CoV-2, we examined …
of virus RNA in single-cell transcriptomes. For these analyses, we used published single-cell

SARS-CoV-2 cell tropism and multiorgan infection

J Liu, Y Li, Q Liu, Q Yao, X Wang, H Zhang, R Chen… - Cell discovery, 2021 - nature.com
SARS-CoV-2 exploits the host angiotensin-converting enzyme 2 (ACE2) as its receptor for
cell entry … that SARS-CoV-2 largely exploits ACE2 as receptor for cell entry in multiple organs. …