… the SARS-CoV-2 receptor binding domain. (A) Location of residues N501, E484 and K417
indicated by blue spheres at the interface of SARS-CoV-2 receptor … of different SARS-CoV-2 …

… Enhanced receptor binding by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
is believed to contribute to the highly contagious transmission rate of coronavirus …

… syndrome coronavirus 2 (SARS-CoV-2) had infected more than 116 million patients …
coronavirus disease 2019 (COVID-19) (https://covid19.who.int). The high infectivity of SARS-CoV-2 …

… in SARS-CoV-2 convalescent sera. Here we show that immunization with the SARS-CoV-2 …
to 100 µg/ml of ACE2-Ig, a potent SARS-CoV-2 entry inhibitor. Importantly, anti-sera from …

… Third, the L486F, Y493Q and D501N residue changes from RaTG13 to SARS-CoV-2
enhance ACE2 recognition and may have facilitated the bat-to-human transmission of …

… The enhanced receptor engagement may account for the increased transmissibility. The B.…
how SARS-CoV-2 has evolved to enhance viral fitness and immune evasion. The COVID-19 …

… higher affinity of SARS-CoV-2 toward the human host ACE2 receptor, … SARS-CoV-2’s
entrance into the host cells. The very first step of SARS viral infection is, indeed, the ACE2 receptor …

… from the RBD, the SARS-CoV-2 polybasic cleavage sites enhance, via electrostatic interactions
… Our work enhances understanding of the binding mechanism of SARS-CoV-2 to ACE2, …

… treatment did not enhance pseudotype entry in the absence of host receptor (Fig. 5). …
Taken together with our receptor assay results, it may be possible that SARS-CoV-2 arose from …

… the receptor-binding domain (RBD) of the spike protein of these SARS-CoV-2 variants
may enhance binding to the human angiotensin-converting enzyme 2 (hACE2). However, no …