[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

Cell entry mechanisms of SARS-CoV-2

J Shang, Y Wan, C Luo, G Ye, Q Geng… - Proceedings of the …, 2020 - National Acad Sciences
… in SARS-CoV-2 entry, we performed pseudovirus entry assay … First, SARS-CoV-2 pseudovirus
entry into all three types of … TMPRSS2 molecules activate SARS-CoV-2 entry. Second, …

Cell entry by SARS-CoV-2

R Peng, LA Wu, Q Wang, J Qi, GF Gao - Trends in biochemical sciences, 2021 - cell.com
… with SARS-CoV-2 S protein and serve as potential alternative/auxiliary attachment
receptors/coreceptors to facilitate SARS-CoV-2 entry into … events during SARS-CoV-2 entry which …

Inhibitors of SARS-CoV-2 entry: current and future opportunities

S Xiu, A Dick, H Ju, S Mirzaie, F Abdi… - Journal of medicinal …, 2020 - ACS Publications
… efforts in designing entry inhibitors against SARS-CoV, MERS-CoV, and other coronaviruses
that can provide important information to combat the current SARS-CoV-2 outbreak. …

Structural and functional basis of SARS-CoV-2 entry by using human ACE2

Q Wang, Y Zhang, L Wu, S Niu, C Song, Z Zhang, G Lu… - Cell, 2020 - cell.com
… of a novel coronavirus (SARS-CoV-2) in China has … entry receptor for SARS-CoV-2. In
this study, we present the crystal structure of the C-terminal domain of SARS-CoV-2 (SARS-CoV-2-…

Role of host factors in SARS-CoV-2 entry

JP Evans, SL Liu - Journal of Biological Chemistry, 2021 - ASBMB
… In addition, we identify the gaps in understanding of SARS-CoV-2 entry that will need to be
… related to SARS-CoV-2 entry and place them in the context of prior coronavirus research as …

[HTML][HTML] Coronavirus entry: how we arrived at SARS-CoV-2

GR Whittaker, S Daniel, JK Millet - Current opinion in virology, 2021 - Elsevier
… Here we review coronavirus entry as a foundation for current work on SARS-CoV-2. We focus
… We also address aspects of the entry process important for virus evolution and therapeutic …

Existence of SARS-CoV-2 entry molecules in the oral cavity

W Sakaguchi, N Kubota, T Shimizu, J Saruta… - International journal of …, 2020 - mdpi.com
… These data showed that essential molecules for SARS-CoV-2 infection were … entry route
for SARS-CoV-2, other factors including protease inhibitors in the saliva that inhibit viral entry

ACE2: the major cell entry receptor for SARS-CoV-2

F Scialo, A Daniele, F Amato, L Pastore, MG Matera… - Lung, 2020 - Springer
… ) [1], and more recently the novel infection named COVID-19, … , SARS-CoV, MERS-CoV and
SARS-CoV-2, respectively [2]. … (ACE)2 that is used by SARS-CoV-2 to gain entry into human …

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

M Letko, A Marzi, V Munster - Nature microbiology, 2020 - nature.com
… We show that host protease processing during viral entry is a significant … entry into
human cells, and confirm that human ACE2 is the receptor for the recently emerging SARS-CoV-2