[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape

WT Harvey, AM Carabelli, B Jackson… - Nature Reviews …, 2021 - nature.com
coronavirus 2 (SARS-CoV-2) … of SARS-CoV-2 in late 2019 was followed by a period of
relative evolutionary stasis lasting about 11 months. Since late 2020, however, SARS-CoV-2

[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
coronavirus 2 (SARS-CoV-2) exhibited a major step change in its adaptation to humans.
These highly mutated forms of SARS-CoV-2 … and antigenicity of SARS-CoV-2 variants, the role …

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Y Cao, J Wang, F Jian, T Xiao, W Song, A Yisimayi… - Nature, 2022 - nature.com
… been identified from SARS-CoV-2 convalescent individuals and … SARS-CoV-2 and
human humoral immunity. Indeed, we showed that Omicron would escape most of the SARS-CoV-2

[HTML][HTML] SARS-CoV-2 variants B. 1.351 and P. 1 escape from neutralizing antibodies

M Hoffmann, P Arora, R Groß, A Seidel, BF Hörnich… - Cell, 2021 - cell.com
… to antibodies used for COVID-19 treatment. Moreover, entry of … COVID-19 patients and sera
from BNT162b2-vaccinated individuals. These results suggest that SARS-CoV-2 may escape

Increased immune escape of the new SARS-CoV-2 variant of concern Omicron

J Hu, P Peng, X Cao, K Wu, J Chen, K Wang… - Cellular & Molecular …, 2022 - nature.com
… infected by SARS-CoV-2 original strain … SARS-CoV-2 variant Omicron S protein with a
large number of mutations has an outstanding effect on the viral infectivity and immune escape

Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera

D Zhou, W Dejnirattisai, P Supasa, C Liu, AJ Mentzer… - Cell, 2021 - cell.com
The race to produce vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
began when the first sequence was published, and this forms the basis for …

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

Y Weisblum, F Schmidt, F Zhang, J DaSilva, D Poston… - elife, 2020 - elifesciences.org
… To select SARS-CoV-2 S variants that escape neutralization by antibodies, we used a …
encodes the SARS-CoV-2 spike (S) protein and green fluorescent protein (rVSV/SARS-CoV-2/GFP…

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
… samples from COVID-19 vaccine recipients or individuals who have recovered from COVID-19.
… Sera from COVID-19-convalescent patients collected 6 or 12 months after symptoms …

SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma

E Andreano, G Piccini, D Licastro… - Proceedings of the …, 2021 - National Acad Sciences
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in … neutralizing plasma from a
COVID-19 convalescent patient. … suggests that SARS-CoV-2 has the potential to escape an …

[HTML][HTML] Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

WF Garcia-Beltran, EC Lam, KS Denis, AD Nitido… - Cell, 2021 - cell.com
… 10 globally circulating strains of SARS-CoV-2. Five of the 10 … SARS-CoV and bat-derived
WIV1-CoV, suggesting that a relatively small number of mutations can mediate potent escape