[HTML][HTML] Colchicine and SARS-CoV-2: management of the hyperinflammatory state

A Vitiello, F Ferrara - Respiratory Medicine, 2021 - Elsevier
… contributor to the adverse outcomes of COVID-19. Several studies have shown that blocking
… this hyperinflammatory state. The search for effective management strategies for COVID-19

Could SARS-CoV-2-induced hyperinflammation magnify the severity of coronavirus disease (CoViD-19) leading to acute respiratory distress syndrome?

ASS Girija, EM Shankar, M Larsson - Frontiers in immunology, 2020 - frontiersin.org
… individuals with CoViD-19 have not developed ARDS. The median time from development
of symptomatic disease to death from CoViD-19 is ~2–8 weeks (3). SARS-CoV-2 appears to …

Inflammatory syndromes associated with SARS-CoV-2 infection: dysregulation of the immune response across the age spectrum

JE Weatherhead, E Clark, TP Vogel… - The Journal of …, 2020 - Am Soc Clin Investig
… compared with adults with COVID-19–associated hyperinflammatory syndrome. Despite
these differences, the hyperinflammatory states that characterize severe COVID-19 and MIS-C/A …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
hyperinflammatory states. Virally associated causes of particular relevance are the 2003 SARS
coronavirus (SARS-CoV) … respiratory syndrome (MERS) coronavirus (MERS-CoV) with a …

The four horsemen of a viral Apocalypse: The pathogenesis of SARS-CoV-2 infection (COVID-19)

P Domingo, I Mur, V Pomar, H Corominas… - …, 2020 - thelancet.com
… The result is a hyperinflammatory and hypercoagulable stateCOVID-19 pathogenesis, and
how SARS-CoV-2 infection and the host response depict the different scenarios of COVID-19

SARS-CoV-2–induced Kawasaki-like hyperinflammatory syndrome: a novel COVID phenotype in children

F Licciardi, G Pruccoli, M Denina, E Parodi… - …, 2020 - publications.aap.org
SARS-CoV-2 cases have spread rapidly throughout China and worldwide, leading the World
Health Organization to declare a pandemic statetwo cases of severe hyperinflammation

SARS-CoV-2 infections in children and young people

S Felsenstein, CM Hedrich - Clinical immunology, 2020 - Elsevier
… Though recent reports link COVID-19 with hyperinflammatory states in children, most CYP …
[2]. Associations between old age and severe disease mirror reports from the SARS epidemic …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARSCoV2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
… -CS, is the primary etiology of multiple organ failure and death brought on by SARS-CoV-2
infection. The function of glucocorticoids in controlling the hyperinflammatory state of COVID-…

Distinct clinical and immunological features of SARSCoV-2–induced multisystem inflammatory syndrome in children

PY Lee, M Day-Lewis, LA Henderson… - The Journal of …, 2020 - Am Soc Clin Investig
… a parallel COVID-19–associated hyperinflammatory state in … to known syndromes of
hyperinflammation and cytokine storm … associated with COVID-19 is a hyperinflammatory

Hyperinflammatory response in COVID-19: a systematic review

MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
… It is worth mentioning that, in COVID-19, due to the interaction of the virus with the host, in …
that influences the creation of a hyperinflammatory state caused by the “cytokine storm”, …