… Exhaustion, indeed, is a state in which cells show … during the progression of SARS-CoV-2
infection could also be … by restraining hyperinflammation) observed in COVID-19 patients, …

… The hyper-inflammatory state observed in COVID-19 patients with a fatal outcome
implies a failure in the negative feedback mechanisms that should restrain the devastating …

… Clinically, the finding of elevated CRP, cytokines IL-6, IL-8, and TNFα in our patients are also
consistent with a hyperinflammatory state, and are part of the mechanism of injury in ARDS …

… The T-cell composition of surviving lymphocytes may exacerbate the hyperinflammatory
state in COVID-19. In conjunction with IL-6– and GM-CSF–producing monocytes, patients with …

… cases of severe systemic hyperinflammation and shock epidemiologically linked with COVID-19
have been reported. This condition was named as SARS-Cov-2-associated multisystem …

… managing MIS-C and hyperinflammation in acute SARS–CoV-2 infection. The multidisciplinary
task force was composed of clinicians from the United States and Canada and included 9 …

REVIEW Mechanisms and potential therapeutic targets of hyperinflammatory responses in
SARS-CoV-2 Page 1 REVIEW Mechanisms and potential therapeutic targets of …

… to a hyper-inflammatory response are in line with COVID-19 disease severity. We propose
that SARS-CoV-2 … /macrophages and create a hyper-inflammatory state leading to enhanced …

… induces eosinopenia is unclear, but it could be due to several factors such as a
hyperinflammatory state that could modulate the eosinophil response, a blockade of eosinophil …

… Coronavirus disease 2019 (COVID-19) is caused by the single-stranded enveloped RNA virus
SARS-CoV‑2. … SARS-CoV‑2 is the seventh human coronavirus, which affects primarily the …