Advances and gaps in SARS-CoV-2 infection models

C Muñoz-Fontela, L Widerspick, RA Albrecht… - PLoS …, 2022 - journals.plos.org
… ) of COVID-19 vaccines that are currently being deployed [2–5… and importance of the use of
animal models for COVID-19. … of SARS-CoV-2 infection and their role in COVID-19 research …

How does SARS-CoV-2 cause COVID-19?

NJ Matheson, PJ Lehner - Science, 2020 - science.org
… -converting enzyme 2 (ACE2) for cell entry (1). The interaction between SARS-CoV-2 and
ACE2 … and progression from early SARS-CoV-2 infection to severe coronavirus disease 2019 (…

The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?

RJ Boyton, DM Altmann - Nature Reviews Immunology, 2021 - nature.com
… Early in the COVID-19 pandemic it became clear that infection with … coronavirus 2 (SARS-CoV-2)
would pose greater challenges to infection control than infection with SARS-CoV in …

[HTML][HTML] Evaluation of K18-hACE2 mice as a model of SARS-CoV-2 infection

GB Moreau, SL Burgess, JM Sturek… - The American journal …, 2020 - ncbi.nlm.nih.gov
… In this report, we have described the course of SARS-CoV-2 infection in K18-hACE2 …
successful infection with SARS-CoV-2 and a milder disease severity compared with SARS-CoV-1. …

Clinical characteristics of hospitalized patients with SARSCoV2 infection: a single arm meta‐analysis

P Sun, S Qie, Z Liu, J Ren, K Li… - Journal of medical …, 2020 - Wiley Online Library
… characteristics and mortality of patients with SARS-CoV-2 infection, we searched the relevant
… on the prevention and treatment of SARS-CoV-2 infection. 2 MATERIAL AND METHODS …

[PDF][PDF] A SARS-CoV-2 infection model in mice demonstrates protection by neutralizing antibodies

AO Hassan, JB Case, ES Winkler, LB Thackray… - Cell, 2020 - cell.com
… type I IFN blockade was not necessary or sufficient for SARSCoV-2 infection in mice, we
observed greater weight loss and lung pathology in the absence of intact IFN signaling. The …

[HTML][HTML] Oral vesiculobullous lesions associated with SARSCoV2 infection

CM Carreras‐Presas, JA Sánchez… - Oral diseases, 2021 - ncbi.nlm.nih.gov
… We here present three cases associated with this virus: two where there is a suspicion of
COVID19 and one case of confirmed infection. All cases presented ulcers or blisters in the oral …

Daily longitudinal sampling of SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness

R Ke, PP Martinez, RL Smith, LL Gibson, A Mirza… - Nature …, 2022 - nature.com
… acute SARS-CoV-2 infection in 60 … infectious virus shedding (from mid-turbinate nasal
swabs) for up to 14 days. We reveal a striking degree of individual-level heterogeneity in infectious

[PDF][PDF] Estimated SARS-CoV-2 Seroprevalence in the US as of September 2020

KL Bajema, RE Wiegand, K Cuffe, SV Patel… - JAMA internal …, 2021 - jamanetwork.com
… We found that most people in the US did not have evidence of previous SARSCoV-2 infection.
This is consistent with other large-scale seroprevalence surveys conducted in the US,10,…

Neurological aspects of SARS-CoV-2 infection: mechanisms and manifestations

P Guadarrama-Ortiz, JA Choreno-Parra… - Frontiers in …, 2020 - frontiersin.org
… human infection of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Although coronavirus disease 2019 (COVID-19), which is associated with this virus, mainly …