… -CoV-2 life cycle. In this Review, we summarize insights into the proviral host factors that are
required for SARS-CoV-2 infection … that are important for the SARS-CoV-2 life cycle, as well …

… of SARS-CoV-2 entry into the cell, which determines host- … findings on the factors governing
SARS-CoV-2 entry. We first … and host cell membrane through binding to the SARS-CoV-2 …

… host-virus genetic dependencies and find potential therapeutic targets for COVID-19, we …
function screen to identify host factors required for SARSCoV-2 viral infection of human alveolar …

… -CoV), bat CoV HKU5 expressing the SARS-CoV-1 spike, and vesicular stomatitis virus (VSV)
expressing the SARS-CoV-2 spike. We identified known SARSCoV-2 host factors, …

… pollution and SARS-CoV-2 infection, as more severe COVID-19 … risk factors for severe
COVID-19 strongly encourage the virus/… and smoking associated risk factors share underlying …

… role of primary host factors such as the cell receptor angiotensin-converting enzyme 2 (ACE2…
, and their pharmacological intervention in the infection of SARS-CoV-2 and related viruses. …

… Lymphocytopenia on admission was another risk factor associated with severe COVID-19
infection in this study. In the dynamic profile of laboratory markers as shown in Figure 1, we …

… network in the acquisition of the infection and the development of the diseases. … SARS-CoV-2
infection as well as the host factors involved in the facilitation and worsening of the infection…

… In summary, our study presents a screen for host factors carried out in a TMPRSS2-positive
genetic background. It therefore unveils host factors critical for SARS-CoV-2 infection that …

… SARS-CoV-2 Host Factors We also identified host factors and pathways that appear to be
required for SARS-CoV-2 infection but less so for other CoVs tested. Genes in the mevalonate …