SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies

CO Barnes, CA Jette, ME Abernathy, KMA Dam… - Nature, 2020 - nature.com
… structural correlates of SARS-CoV-2 neutralization, we solved eight new structures of distinct
COVID-19 human neutralizing antibodies 5 in complex with the SARS-CoV-2 spike trimer …

[HTML][HTML] Human neutralizing antibodies elicited by SARS-CoV-2 infection

B Ju, Q Zhang, J Ge, R Wang, J Sun, X Ge, J Yu… - Nature, 2020 - nature.com
… RBD-specific monoclonal antibodies derived from single B cells from 8 individuals infected
with SARS-CoV-2. We identified antibodies that potently neutralize SARS-CoV-2; this activity …

Neutralizing antibody titres in SARS-CoV-2 infections

EHY Lau, OTY Tsang, DSC Hui, MYW Kwan… - Nature …, 2021 - nature.com
… Age did not appear to compromise antibody responses, even … SARS-CoV-2 infection elicits
robust neutralizing antibody … that SARS-CoV-2 infection elicits robust neutralizing antibody

SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment

D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
… that have antibody-escape mutations and the potential for antibody-… representative
SARS-CoV-2 neutralizing antibodies that have … of COVID-19 preventive or therapeutic antibodies. …

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Y Cao, J Wang, F Jian, T Xiao, W Song, A Yisimayi… - Nature, 2022 - nature.com
… arms race between SARS-CoV-2 and human humoral immunity. Indeed, we showed that
Omicron would escape most of the SARS-CoV-2 neutralizing antibodies in this collection (…

Neutralizing antibodies against SARS-CoV-2 variants after infection and vaccination

VV Edara, WH Hudson, X Xie, R Ahmed, MS Suthar - Jama, 2021 - jamanetwork.com
… Our results also suggest that SARS-CoV-2 subspecies with the RBD mutations Y453F …
neutralizing monoclonal antibodies and 21 neutralizing antibodies in sera derived from COVID-19-…

Robust neutralizing antibodies to SARS-CoV-2 infection persist for months

A Wajnberg, F Amanat, A Firpo, DR Altman, MJ Bailey… - Science, 2020 - science.org
COVID-19 symptoms to determine the robustness and longevity of the anti–SARS-CoV-2
antibody response. They found that neutralizing antibody titers against the SARS-CoV-2 spike …

Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike

L Liu, P Wang, MS Nair, J Yu, M Rapp, Q Wang, Y Luo… - Nature, 2020 - nature.com
coronavirus. Here we report the isolation of sixty-one SARS-CoV-2-neutralizing monoclonal
antibodies from five patients infected with SARS-CoV-2 and admitted to hospital with severe …

SARS-CoV-2 neutralizing antibody LY-CoV555 in outpatients with Covid-19

P Chen, A Nirula, B Heller, RL Gottlieb… - … England Journal of …, 2021 - Mass Medical Soc
… phase 2 trial involving outpatients with recently diagnosed mild or moderate Covid-19, we
… to receive a single intravenous infusion of neutralizing antibody LY-CoV555 in one of three …

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

Y Weisblum, F Schmidt, F Zhang, J DaSilva, D Poston… - elife, 2020 - elifesciences.org
… -SARS-CoV-2 agents. However, the degree to which SARS-CoV-2 will adapt to evade
neutralizing antibodies … chimeric VSV/SARS-CoV-2 reporter virus, we show that functional SARS-…