… infection route and host immune response to SARS-CoV-2, as well as testing vaccines and
… NHP models currently available for SARS-CoV-2, and to discuss key topics including model …

… Disease features not expressed in current animal models include ARDS, … model for
SARS-CoV-2 research. Using NHPs has several drawbacks as compared with small animal models, …

… of SARS-CoV-2 … of SARS-CoV-2 pathogenesis in NHP models discussed in this section
are summarized in Figure 1. The contribution of NHP models to the development of COVID-19 …

… By using high-resolution microscopy, we investigated whether SARS-CoV-2 reaches the …
in a non-human primate model of COVID-19. Seven days after infection, SARS-CoV-2 was …

… Non-human primates infected with SARS-CoV-2 develop a mild infection resembling
asymptomatic human infection. Here we used viral dynamic modelling to characterize the …

… Age and gender may not affect the infection of SARS-CoV-2 in these monkeys. The non-human
primate model in this study recapitulates several clinical features of COVID-19. …

… chest radiograph of our model simulate two typical clinical signs in COVID-19 patients, fever
… for the diagnosis of COVID-19 due to SARS-CoV-2 infection. Genomic SARS-CoV-2 RNA is …

… SARS-CoV-2 vaccine candidates. For example, SARS-CoV and MERS-CoV mouse models,
using … Exacerbated innate host response to SARS-CoV in aged non-human primates. PLoS …

… of a low-passage SARS-CoV-2 isolate in two macaque models and suggests 60 that both
species represent an equally good model in research for both COVID-19 prophylactic 61 and …

… or administration of a SARS-CoV-2 vaccine are … non-human primates (NHPs) from SARS-CoV-2
infection may inform the clinical development of medical countermeasures for COVID-19.…