… receptor recognition and evolution of SARS-CoV-2. We will first discuss how well SARS-CoV-2
recognizes ACE2 in comparison to SARS-CoV. … with SARS-CoV, the SARS-CoV-2 RBM …

… of the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 bound to the cell
receptor … ACE2-binding mode of the SARS-CoV-2 RBD is nearly identical to that of the SARS-…

… ) and the human respiratory coronavirus NL63. Recent studies and analyses indicate that
ACE2 could be the host receptor for the novel coronavirus 2019-nCoV/SARS-CoV-2 1,2 . …

… different susceptibility to and severity of SARS-CoV-2 infection. Strangely, in the … SARS-CoV-2
infection (Chai et al., 2020). Since ACE2 as a confirmed host cell receptor for SARS-CoV-2 …

… As ACE2 is the only currently known SARS‐CoV‐2 receptor on the host cell surface, we …
for SARS‐CoV‐2 infection. Future studies both using in vitro approaches and COVID‐19 patient …

… In sum, the identification of ASGR1 and KREMEN1 as SARS-CoV-2 receptors advances
our understanding of SARS-CoV-2 cell tropism and pathogenesis. Further, this finding …

… to serve as alternative receptors for SARS-CoV and SARS-CoV-2. These include C-type …
to be alternative SARS-CoV-2 receptors 112,113 . As members of phosphatidylserine receptor …

… ) by cleavage between S1 and S2 following receptor binding or trypsin treatment. In most
SARS-CoV-2 sequences, a furin protease cleavage site is inserted between the S1 and S2 …

… They further demonstrated that SARS-CoV-2 does not use other coronavirus receptors such
as … , the SARS-CoV-2 spike protein directly binds with the host cell surface ACE2 receptor …

… Given that ACE2 serves as the receptor for SARS-CoV-2, our findings suggest a potential
mechanism of reduced COVID-19 severity in patients with respiratory allergies. However, it is …