A Ali, R Vijayan - Scientific reports, 2020 - nature.com
… the interaction between SARS-CoV/SARS-CoV-2 and ACE2. … the interactions between SARS-CoV-2/SARS-CoV and ACE2 … interactions that define the ACE2–SARS-CoV-2 and ACE2–…
S Kim, Y Liu, Z Lei, J Dicker, Y Cao… - Journal of chemical …, 2021 - ACS Publications
… ) variant is relatively easily detached from ACE2. Our results from both SMD simulations … ACE2interactions. This study could shed light on developing new drugs to inhibit SARS-CoV-2 …
M Hussain, N Jabeen, F Raza, S Shabbir… - Journal of medical …, 2020 - Wiley Online Library
… and molecular superimposition revealed important variations in the intermolecular interaction between ACE2 alleles and SARS-CoV-2spike protein. It is interesting to note that for two …
A Choudhury, S Mukherjee - Journal of medical virology, 2020 - Wiley Online Library
… of the spike protein of SARS-CoV-2 with the ACE2 receptor … interactions between spike protein and its receptor (ACE2) from … spike protein-bat ACE2 > spike protein-human ACE2 > spike …
M Ejemel, Q Li, S Hou, ZA Schiller, JA Tree… - Nature …, 2020 - nature.com
… Interestingly, our results show that despite the same blocking of spikeinteraction with ACE2, MAb362 IgG weakly neutralizes SARS-CoV-2, whereas IgA as monomer, dimer, or …
P Zhao, JL Praissman, OC Grant, Y Cai, T Xiao… - Cell host & …, 2020 - cell.com
… polypeptide epitopes and directly modulating Spike-ACE2interactions. Furthermore, our … on Spike glycosylation, as well as the influence of natural variants on ACE2 receptor …
J Lan, J Ge, J Yu, S Shan, H Zhou, S Fan, Q Zhang… - nature, 2020 - nature.com
… the interaction between the SARS-CoV-2 RBD and ACE2 at … that the SARS-CoV-2 RBD–ACE2 and SARS-CoV RBD–ACE2 … of interacting residues and hydrophilic interaction networks, …
KK Chan, D Dorosky, P Sharma, SA Abbasi, JM Dye… - Science, 2020 - science.org
… , mutations in ACE2 that increase S binding are found across the interaction surface, in the … for understanding the specificity of the interaction between ACE2 and S and for engineering …
… ongoing COVID-19 pandemic. Here, we have identified a novel small molecule that inhibited the interactions between SARS-CoV-2spike RBDs and ACE2 by modulating ACE2 without …