[HTML][HTML] Structural and functional analysis of the D614G SARS-CoV-2 spike protein variant

L Yurkovetskiy, X Wang, KE Pascal, C Tomkins-Tinch… - Cell, 2020 - cell.com
… The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide,
reaching … D614G did not alter S protein synthesis, processing, or incorporation into SARS-…

Structure of SARS-CoV-2 spike protein

J Zhang, T Xiao, Y Cai, B Chen - Current opinion in virology, 2021 - Elsevier
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has … structural biology of
SARS-CoV-2 S protein has been made … of the structure of the SARS-CoV-2 S protein and discuss …

Human SARS CoV2 spike protein mutations

L Guruprasad - Proteins: Structure, Function, and Bioinformatics, 2021 - Wiley Online Library
spike proteins from some of the SARS-CoV-2 Indian isolates have been mapped on to protein
… all the mutations present in the human SARS-CoV-2 spike proteins relative to Wuhan-Hu-…

Domains and functions of spike protein in Sars-Cov-2 in the context of vaccine design

X Xia - Viruses, 2021 - mdpi.com
… The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor …
SARS-CoV-2 uses its trimeric spike protein for binding to host angiotensin-converting enzyme 2

The spike protein of SARS-CoV—a target for vaccine and therapeutic development

L Du, Y He, Y Zhou, S Liu, BJ Zheng… - Nature Reviews …, 2009 - nature.com
… on the spike (S) protein of severe acute respiratory syndrome-coronavirus (SARS-CoV) as a
… for the development of vaccines and therapeutics for the prevention and treatment of SARS. …

Distinct conformational states of SARS-CoV-2 spike protein

Y Cai, J Zhang, T Xiao, H Peng, SM Sterling… - Science, 2020 - science.org
… A dynamic viral spike Efforts to protect human cells against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) have focused on the trimeric spike (S) protein. Several …

SARS-CoV-2 spike protein interacts with and activates TLR41

Y Zhao, M Kuang, J Li, L Zhu, Z Jia, X Guo, Y Hu… - Cell research, 2021 - nature.com
… was activated by SARS-CoV-2, we hypothesized that spike protein could activate … SARS-CoV-2
spike proteins are high quality antigens. To this end, we purified the trimeric spike protein

Amyloidogenesis of SARS-CoV-2 spike protein

S Nystrom, P Hammarstrom - Journal of the American Chemical …, 2022 - ACS Publications
SARS-CoV-2 infection is associated with a surprising … the amyloidogenicity of the SARS-CoV-2
spike protein (S-protein). … sequences within the S-protein. All seven peptides in isolation …

Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development

SK Samrat, AM Tharappel, Z Li, H Li - Virus research, 2020 - Elsevier
SARS-CoV or MERS-CoV have been tried with limited success. Since SARS-CoV-2 uses the
spike (S) protein … for making vaccines or therapeutics against SARS-CoV-2. In this review, …

Structural impact on SARS-CoV-2 spike protein by D614G substitution

J Zhang, Y Cai, T Xiao, J Lu, H Peng, SM Sterling… - Science, 2021 - science.org
… Throughout the COVID-19 pandemic, epidemiologists have monitored the evolution of …
respiratory syndrome coronavirus 2 (SARS-CoV-2) with particular focus on the spike protein. An …