Bullous pemphigoid after SARSCoV2 vaccination: spike‐protein‐directed immunofluorescence confocal microscopy and Tcellreceptor studies

T Gambichler, N Hamdani, H Budde… - British Journal of …, 2022 - academic.oup.com
… With respect to the TCR repertoire in lesional skin, we observed a marked clonal expansion
of T cells in both patients with BP, indicating an ongoing adaptive immune response. …

[HTML][HTML] Modeling and predicting the overlap of B-and T-cell receptor repertoires in healthy and SARS-CoV-2 infected individuals

M Ruiz Ortega, N Spisak, T Mora, AM Walczak - PLoS Genetics, 2023 - journals.plos.org
… [75–77]—around 0.15–0.8% of total memory B cells are spike-specific according to [78]. We
… we expect TCR repertoires to be more stable over time, and COVID-19 signatures to persist …

Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2

…, MGH COVID-19 Collection and Processing Team… - Science …, 2021 - science.org
… Of relevance, 85 of these epitopes were derived from the Spike protein currently used in …
landscape of SARS-CoV-2–reactive CD8 + T cells, we asked how TCR repertoires evolve over …

Analysis of B cell receptor repertoires reveals key signatures of the systemic B cell response after SARS-CoV-2 infection

Y Zhang, Q Yan, K Luo, P He, R Hou, X Zhao… - Journal of …, 2022 - Am Soc Microbiol
… and T cell receptor repertoire of COVID-19 patients and found that the percentage of TCR-…
We first determined the antibodies against SARS-CoV-2 spike protein (S) and nucleocapsid …

[HTML][HTML] CoV2-TCR: A web server for screening TCR CDR3 from TCR immune repertoire of COVID-19 patients and their recognized SARS-CoV-2 epitopes

X Jian, Y Zhang, J Zhao, Z Zhao, M Lu, L Xie - Computational and Structural …, 2023 - Elsevier
… This tool required users to select a specific protein from SARS-CoV-2, ie spike glycoprotein
(S), membrane protein (M), envelop protein (E), or nucleocapsid protein (N), and its specified …

[HTML][HTML] Mutations in SARS-CoV-2 spike protein impair epitope-specific CD4+ T cell recognition

EXC Tye, E Jinks, TA Haigh, B Kaul, P Patel… - Nature …, 2022 - nature.com
… infection in an individual might be determined by a complex combination of factors, including
the conservation of the epitopes presented by their HLA genotype, their TCR repertoire and …

Anti-spike T-cell and antibody responses to SARS-CoV-2 mRNA vaccines in patients with hematologic malignancies

LM Greenberger, LA Saltzman, LM Gruenbaum… - Blood cancer …, 2022 - AACR
… In this report, we use sequencing of the T-cell receptor (TCR) repertoire from peripheral
blood and the enrichment of SARS-CoV-2–specific TCRs (10) to characterize T-cell responses …

[HTML][HTML] SARS-CoV-2-specific T-cell epitope repertoire in convalescent and mRNA-vaccinated individuals

J Lang-Meli, H Luxenburger, K Wild, V Karl… - Nature …, 2022 - nature.com
… VOC harbours multiple mutations in the spike protein … of the SARS-CoV-2-specific T-cell
epitope repertoire after infection and messenger RNA vaccination, we demonstrate that spike-…

[HTML][HTML] Utility of bulk T-cell receptor repertoire sequencing analysis in understanding immune responses to COVID-19

H Kockelbergh, S Evans, T Deng, E Clyne… - Diagnostics, 2022 - mdpi.com
… infection is confounded by T-cell cross-reactivity with seasonal coronaviruses, with a study
demonstrating cross-reactive T cells against the spike protein of SARS-CoV-2 in 28% of …

Repeated mRNA vaccination sequentially boosts SARS-CoV-2-specific CD8+ T cells in persons with previous COVID-19

ES Ford, K Mayer-Blackwell, L Jing, KJ Laing… - Nature …, 2024 - nature.com
… of spike-reactive T (T S ) cells from SARS-CoV-2 infection … , we identified the T cell receptor
(TCR) sequences of thousands … TCR repertoires in general, and the response to SARS-CoV-…