… The 3C-like (or Main) protease (3CL pro ) and the nsp12 RNA-dependent RNA-polymerase
(RdRp) are the best characterized SARS-CoV-2 targets and show the highest degree of …

… the strategies and targets currently adopted in developing a vaccine against SARS-CoV-2. …
ADE viral entry into the target cell of SARS-CoV-2 is mediated by the Fc receptor II and not by …

… The effects of SARS-CoV-2 on the immune system on cytokine production and T-cells, … the
disease severity of COVID-19 in the older patient. While larger studies of COVID-19 in elderly …

… It also targets the ASP761, ALA762, LYS798, and SER814 residues with stout hydrogen …
structurally similar to Galidesivir that may target SARS-CoV-2 RdRp as an antiviral agent. The …

… It is known that the respiratory system is a major target of SARS-CoV-2. Recent studies
showed that SARS-CoV-2 targets ciliated and AT2 cells in airway and alveolar regions 2 , and …

… 2 (ACE2), the main host cell receptor of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), … of dysgeusia in patients with COVID-19. Hence, it is important to understand if …

… shown that it has acitivity against SAR COV 2 S-glycoprotein and proteas(M pro ) targets
making it a drug to be considered with multi-target ability in the management of this disease. …

… coronavirus disease 2019 (COVID-19), caused by novel severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)… drug targets being used inhibit entry and fusion of SARS-CoV-2 …

… SARS-CoV-2 infection and uncover a mechanism of action. We show that imatinib inhibits
the infection of SARS-CoV-2 … fusion mediated by the SARS-CoV-2 surface protein, Spike, and …

… Schematic diagram of SARS-CoV-2 life cycle and potential antiviral drug targets based
on life cycle. SARS-CoV-2 life cycle comprises several stages. 1) Attachment of the viral S …