R Kircheis - International journal of molecular sciences, 2021 - mdpi.com
… SARS-CoV-2 encapsulated in lipid nanoparticles and two adenoviralvector-based vaccines, ie, ChAdOx1 nCoV… chimpanzee adenoviralvector encoding the spike protein of SARS-CoV-…
… events of adenovirusvector or of SARS-CoV-2 RNA reverse transcript DNA at low frequency versus hopefully high vaccine efficacy and protection. Moreover, since SARS-CoV-2 …
S Wu, G Zhong, J Zhang, L Shuai, Z Zhang… - Nature …, 2020 - nature.com
… replication-defective human type 5 adenovirus encoding the SARS-CoV-2 spike protein (Ad5-nCoV) protect mice completely against mouse-adapted SARS-CoV-2 infection in the upper …
T Tada, H Zhou, MI Samanovic, BM Dcosta… - BioRxiv, 2021 - biorxiv.org
… mRNA-based and an adenoviralvector-based vaccine against … acute respiratory syndrome coronavirus 2 (SARS-CoV-2) … (Pfizer and Moderna) and adenoviralvector-based (Johnson & …
JG Mulhern, A Fadia, R Patel… - Clinical Journal of the …, 2021 - journals.lww.com
Patients on maintenance dialysis may be immunocompromised and have comorbidities that modulate the response to coronavirus disease 2019 (COVID-19) vaccines. We conducted a …
… facility for intranasal instillation of non-replicating adenoviral (Ad) vectors before being transferred to a BSL-3 facility at ISMMS for challenge with SARS-CoV-2. Mice were housed under …
CCD Joe, J Jiang, T Linke, Y Li… - Biotechnology and …, 2022 - Wiley Online Library
… ChAdOx1 nCoV-19 (AZD1222, Vaxzevria) is an efficacious vaccine against SARS-CoV-2, based upon an adenovirusvector. We describe the development of a process for the …
… -2 spike protein was detected only in the ChAdOx1 nCoV-19 vaccine. There may be several … of the SARS-CoV-2 transgene during the production of the recombinant adenoviralvectors. …
T Tada, H Zhou, MI Samanovic, BM Dcosta… - Frontiers in …, 2022 - frontiersin.org
The increasing prevalence of SARS-CoV-2 variants has raised concerns regarding possible decreases in vaccine effectiveness. Here, neutralizing antibody titers elicited by mRNA-…