… respiratory syndrome coronavirus (SARS-CoV) structural … the adenovirus-mediated
over-expression of SARS-CoV spike (S) … of S and S2 protein in SARS-CoV induced apoptosis and …

… ) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to …
adenovirus (Ad) vector platforms have been leveraged in response to this pandemic. Ad vectors …

… The infectivity of the original emergent SARS-CoV-2 strain was close to or slightly higher …
coronavirus 1 (SARS-CoV-1), and it is highly antigenically and genetically similar to SARS-CoV-…

… adenovirus vectored mouse IFN alpha gene (mDEF201) as a prophylactic and treatment
countermeasure in a SARS-CoV… , 7, or 14 days prior to lethal SARS-CoV challenge (p < 0.001), …

… of high-dose SARS-CoV-2 infection in hamsters and evaluated the protective efficacy of
an adenovirus serotype 26 (Ad26) vector-based vaccine 19 encoding a stabilized SARS-CoV-2 …

… syndrome coronavirus 2 (SARS-CoV-2) and severe coronavirus disease 2019 (COVID-19)
manifestation. As such, efforts to vaccinate these patients and understand the effectiveness of …

… Studies have suggested that SARS-CoV-2 vaccines that use an adenoviral vector platform
may be related to the occurrence of thrombotic thrombocytopenia [15,16,17]. During early to …

… SARS-CoV-2 antigens onto a chimeric adenovirus 5/35 platform that was effective in cellular
immunity. By replacing the S1/S2 furin cleavage sequence of the SARS-CoV… the adenovirus-…

… , replication-incompetent human adenovirus type 26 vector encoding a full-length,
membrane-bound severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein in a …

… However, viral vector–based vaccines that incorporate viruses other than SARS-CoV-2
are in advanced-phase studies, including adenovirus (AdV) vector–based vaccines that have …