[HTML][HTML] Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets
ME Francis, B Richardson, M McNeil, M Rioux… - bioRxiv, 2021 - ncbi.nlm.nih.gov
… nasal turbinates positive for SARS-CoV-2 were delayed in aged male ferrets but … SARS-CoV-2-infected
aged male ferrets, we performed unbiassed, whole transcriptome transcriptome …
aged male ferrets, we performed unbiassed, whole transcriptome transcriptome …
Blood transcriptomes of SARS-CoV-2 infected kidney transplant recipients demonstrate immune insufficiency
… We evaluated the peripheral blood transcriptome of 64 KTRs either during or after acute
COVID-19. We identified transcriptomic signatures consistent with suppression of adaptive T-…
COVID-19. We identified transcriptomic signatures consistent with suppression of adaptive T-…
Clonal chromosomal mosaicism and loss of chromosome Y in men are risk factors for SARS-CoV-2 vulnerability in the elderly
… rates, and mortality stratified by age and sex was obtained from this report. Prevalence …
individuals with LOY compared to those without LOY using bulk transcriptome data (Table S7). …
individuals with LOY compared to those without LOY using bulk transcriptome data (Table S7). …
[HTML][HTML] Co-expression of the SARS-CoV-2 entry molecules ACE2 and TMPRSS2 in human ovaries: identification of cell types and trends with age
M Wu, L Ma, L Xue, Q Zhu, S Zhou, J Dai, W Yan… - Genomics, 2021 - Elsevier
… Next, we validated the results of transcriptome analysis by using immunohistochemistry in
human ovaries. Immunoreactivity for ACE2 was found to be distributed in multiple regions of …
human ovaries. Immunoreactivity for ACE2 was found to be distributed in multiple regions of …
Analysis of transcriptomic responses to SARS-CoV-2 reveals plausible defective pathways responsible for increased susceptibility to infection and complications and …
EJ deAndres-Galiana, JL Fernández-Martínez… - Computers in Biology …, 2022 - Elsevier
… We also show via Principal Component Analysis that the transcriptome … age 72) and one
female (age 60) and lung samples derived from a single male COVID-19 deceased patient (age …
female (age 60) and lung samples derived from a single male COVID-19 deceased patient (age …
Host nasopharyngeal transcriptome dataset of a SARS-CoV-2 positive Italian cohort
A Salvati, C Ferravante, J Lamberti, T Rocco… - Scientific Data, 2023 - nature.com
… COVID-19 disease alters the host transcriptome, affecting cellular … cell transcriptome, we
have generated a dataset from nasopharyngeal swabs of 35 individuals infected with SARS-CoV…
have generated a dataset from nasopharyngeal swabs of 35 individuals infected with SARS-CoV…
Blood transcriptomes of SARS-CoV-2–infected kidney transplant recipients associated with immune insufficiency proportionate to severity
… Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) … factors for disease severity including advanced age and presence of …
coronavirus 2 (SARS-CoV-2) … factors for disease severity including advanced age and presence of …
SARS-CoV-2-Induced Type I Interferon Signaling Dysregulation in Olfactory Networks Implications for Alzheimer's Disease
GD Vavougios, T Mavridis, T Doskas… - Current Issues in …, 2024 - mdpi.com
… route, the pathway by which SARS-CoV-2 may gain entry into … and olfactory bulb amygdala
transcriptomes of COVID-19 … -19 transcriptomes were also present in transcriptomes from …
transcriptomes of COVID-19 … -19 transcriptomes were also present in transcriptomes from …
Developmental aspects of SARS-CoV-2, potential role of exosomes and their impact on the human transcriptome
… Single-cell RNA sequencing of COVID-19 patients aged between 4 weeks to 77 years, …
stark differences in the transcriptomes between the two populations [114]. SARS-CoV-2 infection …
stark differences in the transcriptomes between the two populations [114]. SARS-CoV-2 infection …
AGE IS ASSOCIATED WITH INCREASED EXPRESSION OF PATTERN RECOGNITION RECEPTOR GENES AND ACE2, THE RECEPTOR FOR SARS-COV-2 …
SW Bickler, DM Cauvi, KM Fisch, JM Prieto, AD Gaidry… - bioRxiv, 2020 - biorxiv.org
… expression of ACE2 and TLR4, but also have an aged transcriptome which could be important
for the infectivity and outcome of the SARS-CoV-2 infection. The critical role PRRs play in …
for the infectivity and outcome of the SARS-CoV-2 infection. The critical role PRRs play in …