Clinical validity of serum antibodies to SARS-CoV-2: a case–control study

G Caturegli, J Materi, BM Howard… - Annals of internal …, 2020 - acpjournals.org
Antibodies to SARS-CoV-2 predicted the odds of developing acute respiratory distress
syndrome… Antibodies were present in 5 of 6 case patients and none of the 12 control patients (P = …

[HTML][HTML] Anti-spike antibody response to natural SARS-CoV-2 infection in the general population

J Wei, PC Matthews, N Stoesser, T Maddox… - Nature …, 2021 - nature.com
… Here we estimated antibody response after SARS-CoV-2 … participants who had positive
swab SARS-CoV-2 PCR tests from … Study limitations include the fact that we only measured anti-…

[HTML][HTML] Comparison of six commercially available SARS-CoV-2 antibody assays—Choice of assay depends on intended use

AC Nilsson, DK Holm, US Justesen… - International Journal of …, 2021 - Elsevier
… The detection limit of IgG and IgM assays was compared using a serum sample containing
IgM and IgG SARS-CoV-2 antibodies, two-foldly diluted (1-1,024). The highest titer which …

Analytical and clinical performances of five immunoassays for the detection of SARS-CoV-2 antibodies in comparison with neutralization activity

A Padoan, F Bonfante, M Pagliari, A Bortolami… - …, 2020 - thelancet.com
… The present paper has limitations: first, neutralizing antibodies were tested in a limited
number of samples and sera were collected at various timepoints and, therefore, should be …

SARS-CoV-2 infection induces protective immunity and limits transmission in Syrian hamsters

P Selvaraj, CZ Lien, S Liu, CB Stauft… - Life science …, 2021 - life-science-alliance.org
… of neutralizing antibodies. Altogether, these results show that SARS-CoV-2 infection
induces protective immunity that not only prevents re-exposure but also limits transmission in …

The duration, dynamics and determinants of SARS-CoV-2 antibody responses in individual healthcare workers

SF Lumley, J Wei, D O'Donnell, NE Stoesser… - MedRxiv, 2020 - medrxiv.org
Limitations One limitation of our study was that our cohort of individuals consisted of adults
of working age (17-69 years); further longitudinal studies will be required to investigate …

Antibody titer kinetics and SARS-CoV-2 infections six months after administration with the BNT162b2 vaccine

D Ferrari, N Clementi, E Criscuolo, A Ambrosi, F Corea… - Vaccines, 2021 - mdpi.com
… , nine of which were seropositive at T0 (Table S2), were chosen at T 1 to cover the anti-RBD
titers instrumental range used in this study: 4 were below the 0.4 U/mL detection limit, 36 …

A perspective on potential antibody-dependent enhancement of SARS-CoV-2

AM Arvin, K Fink, MA Schmid, A Cathcart, R Spreafico… - Nature, 2020 - nature.com
SARS-CoV-2, which would limit antibody cross-reactivity. Antibodies to the S proteins of
SARS-CoV and SARS-CoV-2—and, to a much lesser extent, MERS-CoV—can cross-react, and …

Serological signatures of SARS-CoV-2 infection: implications for antibody-based diagnostics

J Rosado, S Pelleau, C Cockram, S Hélène Merkling… - MedRxiv, 2020 - medrxiv.org
… Modelling beyond the timeframe for which we have data has its limitations, however our
approach benefits from robust quantification of uncertainty accounting for a wide range of future …

[HTML][HTML] Antibody response against SARS-CoV-2 spike protein and nucleoprotein evaluated by four automated immunoassays and three ELISAs

J Van Elslande, B Decru, S Jonckheere… - Clinical Microbiology …, 2020 - Elsevier
… There are a number of limitations to our study. First, we only included a limited number of
samples from patients with frequent respiratory infections such as influenza, Mycoplasma …