A highly specific and sensitive serological assay detects SARS-CoV-2 antibody levels in COVID-19 patients that correlate with neutralization

D Peterhoff, V Glück, M Vogel, P Schuster, A Schütz… - Infection, 2021 - Springer
… Of note, mild infections resulted in short-lived and very low antibody titers near the detection
limit. This loss of humoral immunity has been linked to the occurrence of (re-)infections with …

Evaluation of three quantitative anti-SARS-CoV-2 antibody immunoassays

S Chapuy-Regaud, M Miédougé… - Microbiology …, 2021 - Am Soc Microbiol
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) … antibodies directed to the
SARS-CoV-2 Spike (S) antigen, either total (Wantaï SARS-CoV-2 Ab ELISA) or IgG (SARS-CoV-2 …

Analytical and clinical validation of an ELISA for specific SARSCoV‐2 IgG, IgA, and IgM antibodies

M Tré‐Hardy, A Wilmet, I Beukinga… - Journal of medical …, 2021 - Wiley Online Library
coronavirus responsible for the 2003 severe acute respiratory syndrome (SARS) outbreak,
was renamed SARS coronavirus 2 (“SARS… Finally, the present study has some limitations. First…

Influencing factors of anti‐SARSCoV‐2‐spike‐IgG antibody titers in healthcare workers: A cross‐section study

J Reusch, I Wagenhäuser, A Gabel… - Journal of Medical …, 2023 - Wiley Online Library
… This limits the interpretation of the anti-SARS-CoV-2-spike IgG levels of HCWs with immune
deficiency and its consequences on the immune response after COVID-19 vaccination. …

SARS-CoV-2-specific ELISA development

V Roy, S Fischinger, C Atyeo, M Slein, C Loos… - Journal of …, 2020 - Elsevier
… Several antibody tests have emerged to diagnose SARS-CoV-2. Here we report on a …
Limit of detection To determine the limit of detection of the assay, 90 known SARS-CoV-2-RNA-…

Side-by-side comparison of three fully automated SARS-CoV-2 antibody assays with a focus on specificity

T Perkmann, N Perkmann-Nagele, MK Breyer… - Clinical …, 2020 - academic.oup.com
… We conclude that low seroprevalences require an unusually high specificity for SARS-CoV-2
antibody tests, which pushes some test systems to their limits earlier than others. Therefore, …

Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom

J Wei, N Stoesser, PC Matthews, D Ayoubkhani… - Nature …, 2021 - nature.com
… anti-trimeric spike IgG antibody responses after SARS-CoV-2 … , the presence or absence of
prior SARS-CoV-2 infection and … assay upper limit of 500 ng ml –1 . For the logistic model for …

[PDF][PDF] Determinants of passive antibody effectiveness in SARS-CoV-2 infection

E Stadler, KL Chai, TE Schlub, D Cromer… - medrxiv, 2022 - scholar.archive.org
… Despite these limitations, a major strength of our … antibody treatment for SARS-CoV-2.
A major factor that will affect future use of antibody therapies is the recognition of SARSCoV-2 …

Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival

S Dispinseri, M Secchi, MF Pirillo, M Tolazzi… - Nature …, 2021 - nature.com
… Here we profile the antibody responses of 162 COVID-19 symptomatic patients in the
COVID… to find SARS-CoV-2 neutralization, as well as antibodies either recognizing SARS-CoV-2 …

Potently neutralizing and protective human antibodies against SARS-CoV-2

SJ Zost, P Gilchuk, JB Case, E Binshtein, RE Chen… - Nature, 2020 - nature.com
… the antibody-treated groups (limit of detection = 50 (1.7 log 10 ) RNA copies per swab or per
ml), indicating that these antibodies conferred protection against SARS-CoVantibodies were …