… of the SARS-CoV-2 spike protein and have been modified to have an extended half-life. The antibodycombination protected nonhuman primates from infection with SARS-CoV-2 when …
… For cocktails of mAbs consisting of non-competing antibodies that target different regions of SARS-CoV-2 spike protein, resistance was found to occur whenever the combination of …
N Wang, Y Sun, R Feng, Y Wang, Y Guo, L Zhang… - Cell research, 2021 - nature.com
… HB27, are pan-SARS-CoVs cross-reactive and SARS-CoV-2-… conferred effective protection against SARS-CoV-2 in animal … -antibody cocktails of the NTD-targeting FC05 in combination …
MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - Jama, 2022 - jamanetwork.com
… -CoV-2 spike protein receptor–binding domain and block virus entry. The 2-antibody combination reduces the risk of emergence of treatment-induced SARS-CoV-2 variants and retains …
V Dussupt, RS Sankhala, L Mendez-Rivera… - Nature …, 2021 - nature.com
… of neutralizing antibodies elicited by SARS-CoV-2 … SARS-CoV-2-specific CD19 + B cells with a broad range of specificities. The first sorting strategy used a combination of SARS-CoV-2 (…
… , COV2-2130/COV2-2196 and REGN10933/REGN10987 combinations prevented infection and inflammation caused by the different SARS-CoV-2 strains, we tested a tenfold-lower (4 …
… in which B.1.351 and related variants 13,14 are prevalent, and highlight the importance of combinationantibody therapy to address the expanding antigenic diversity of SARS-CoV-2. …
L Wang, T Zhou, Y Zhang, ES Yang, CA Schramm… - Science, 2021 - science.org
… We evaluated these antibodies individually or in combinations for their capacity to prevent rcVSV-SARS2 escape and discovered that antibodycombinations with complementary modes …
KH Liang, PY Chiang, SH Ko, YC Chou, RM Lu… - Journal of Biomedical …, 2021 - Springer
… antibodies and their combinations were confirmed in SARS-… our antibodies in a hamster model of mild human SARS-CoV-… combination (1.5 mg/kg each) were made one day prior to WT …