Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B. 1.1. 529

T Zhou, L Wang, J Misasi, A Pegu, Y Zhang, DR Harris… - Science, 2022 - science.org
… Last, we assessed combinations of monoclonal antibodies and found several, … antibody
combinations that can be used for treatment and have demonstrated how these combinations

[PDF][PDF] A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in cynomolgus macaques

RR Cobb, J Nkolola, P Gilchuk, A Chandrashekar, J Yu… - Med, 2022 - cell.com
… use of an antibody combination that could … SARS-CoV-2 variants of concern. This work
provides evidence for developing a combination of antibodies as prophylaxis against SARS-CoV-…

Humoral immunity to SARS-CoV-2 elicited by combination COVID-19 vaccination regimens

Z Wang, F Muecksch, F Muenn, A Cho… - Journal of Experimental …, 2022 - rupress.org
… -Hu-1 SARS-CoV-2 spike protein (183 and 94 antibodies isolated from AZ/… Memory B cell
antibodies elicited by mRNA, Ad26.… antibodies and RBD, we imaged WT Wuhan-Hu-1 SARS-…

Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

RE Chen, X Zhang, JB Case, ES Winkler, Y Liu… - Nature medicine, 2021 - nature.com
… introduced antibody and vaccine countermeasures. Here, using monoclonal antibodies (…
, we report the impact on antibody neutralization of a panel of authentic SARS-CoV-2 variants …

Efficacy of the combination of monoclonal antibodies against the SARS-CoV-2 Beta and Delta variants

C Boonkrai, TS Cotrone, W Chaisuriyong… - Plos one, 2023 - journals.plos.org
coronavirus 2 (SARS-CoV-2) is currently the biggest healthcare issue worldwide. This study
aimed to develop a monoclonal antibody against SARS-CoV… human monoclonal antibodies (…

A combination of receptor-binding domain and N-terminal domain neutralizing antibodies limits the generation of SARS-CoV-2 spike neutralization-escape mutants

D Haslwanter, ME Dieterle, AZ Wec, CM O'brien… - Mbio, 2021 - Am Soc Microbiol
… These MAb therapeutics are solely targeting the receptor-binding domain of the SARS-CoV-2 …
We report that a combination of two neutralizing antibodies targeting the receptor-binding …

Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains

JB Case, S Mackin, JM Errico, Z Chong… - Nature …, 2022 - nature.com
SARS-CoV-2 Omicron lineage strains (BA.1, BA.1.1, and BA.2) of two monoclonal antibody
… AZD7442 [AstraZeneca] combination), which correspond to ones used to treat or prevent …

An engineered bispecific human monoclonal antibody against SARS-CoV-2

Z Li, S Li, G Zhang, W Peng, Z Chang, X Zhang… - Nature …, 2022 - nature.com
antibodies are a promising therapy. A noncompeting pair of human neutralizing antibodies
(B38 and H4) blocking SARS-CoV-… antibodies, antibody combinations and bsAb using SARS-…

A narrative review of the clinical practicalities of bamlanivimab and etesevimab antibody therapies for SARS-CoV-2

R Nathan, I Shawa, I De La Torre, JM Pustizzi… - Infectious diseases and …, 2021 - Springer
… -19 prevention, neutralizing monoclonal antibodies (mAbs), … severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)… As prevalence of SARS-CoV-2 variants can differ by country …

Monoclonal antibody therapies in the management of SARS-CoV-2 infection

E Miguez-Rey, D Choi, S Kim, S Yoon… - Expert Opinion on …, 2022 - Taylor & Francis
… A broad range of both novel and repurposed therapies have been evaluated as potential
treatments for SARS-CoV-2 infection, to be used in combination with supportive care measures…