Antibody-mediated neutralization of SARS-CoV-2

H Gruell, K Vanshylla, T Weber, CO Barnes, C Kreer… - Immunity, 2022 - cell.com
… of neutralizing antibodies is essential to guide vaccine design strategies as well as antibody-…
findings on SARS-CoV-2 neutralizing antibodies, with a focus on their clinical application. …

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

D Pinto, YJ Park, M Beltramello, AC Walls, MA Tortorici… - Nature, 2020 - nature.com
neutralizing antibodies. Here we describe several monoclonal antibodies that target the S
glycoprotein of SARS-CoV-… acute respiratory syndrome coronavirus (SARS-CoV) in 2003. One …

SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment

D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
… that have antibody-escape mutations and the potential for antibody-… representative
SARS-CoV-2 neutralizing antibodies that have … of COVID-19 preventive or therapeutic antibodies. …

[HTML][HTML] Human neutralizing antibodies elicited by SARS-CoV-2 infection

B Ju, Q Zhang, J Ge, R Wang, J Sun, X Ge, J Yu… - Nature, 2020 - nature.com
… infected with SARS-CoV-2. We identified antibodies that potently neutralize SARS-CoV-2; …
Unexpectedly, the anti-SARS-CoV-2 antibodies and the infected plasma did not cross-react …

Neutralizing antibody titres in SARS-CoV-2 infections

EHY Lau, OTY Tsang, DSC Hui, MYW Kwan… - Nature …, 2021 - nature.com
… Age did not appear to compromise antibody responses, even … SARS-CoV-2 infection elicits
robust neutralizing antibody … that SARS-CoV-2 infection elicits robust neutralizing antibody

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

D Planas, D Veyer, A Baidaliuk, I Staropoli… - Nature, 2021 - nature.com
… We next asked whether vaccine-elicited antibodies neutralized the Delta variant in
individuals who had not previously been infected with SARS-CoV-2. We randomly selected 59 …

SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies

CO Barnes, CA Jette, ME Abernathy, KMA Dam… - Nature, 2020 - nature.com
… the structural correlates of SARS-CoV-2 neutralization, we … neutralizing antibodies 5 in complex
with the SARS-CoV-2 … the antibodies into categories: (1) neutralizing antibodies encoded …

Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B. 1.1. 529

T Zhou, L Wang, J Misasi, A Pegu, Y Zhang, DR Harris… - Science, 2022 - science.org
… To define the impact of SARS-CoV-2 variant amino acid changes on the binding and
neutralization of monoclonal antibodies, we expressed and purified 17 highly potent antibodies

Neutralizing antibodies against SARS-CoV-2 variants after infection and vaccination

VV Edara, WH Hudson, X Xie, R Ahmed, MS Suthar - Jama, 2021 - jamanetwork.com
… suggest that SARS-CoV-2 subspecies with the RBD mutations Y453F or N501Y partially
escaped detection by 4 neutralizing monoclonal antibodies and 21 neutralizing antibodies in …

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
… individuals generated an anti-Omicron neutralizing response, with titres 6-… antibodies and,
to a large extent, vaccine-elicited antibodies. However, Omicron is neutralized by antibodies