[HTML][HTML] Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies

M Yuan, H Liu, NC Wu, IA Wilson - Biochemical and biophysical research …, 2021 - Elsevier
… of the antibody response against SARS-CoV-… antibody recognition of the SARS-CoV-2
RBD. Three major epitopes on the RBD are recognized by the currently characterized SARS-CoV-…

The impact of receptor-binding domain natural mutations on antibody recognition of SARS-CoV-2

C Li, X Tian, X Jia, J Wan, L Lu, S Jiang, F Lan… - … and Targeted Therapy, 2021 - nature.com
… Next, we evaluated the binding breadth of a combination of two antibodies recognizing
antibody 414-1 with non-competing antibody n3130 resulted in full coverage of SARS-CoV-2 …

[PDF][PDF] Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain

AK Wheatley, P Pymm, R Esterbauer, MH Dietrich… - Cell Reports, 2021 - cell.com
… -2 virus entry and ameliorate SARSCoV-2 infection in mice and hamsters. Structural … of
neutralizing antibodies that will be potentially useful in future anti-SARS-CoV-2 therapeutics. …

Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail

J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens… - BioRxiv, 2021 - biorxiv.org
… to understand the molecular basis for immune recognition of SARS-CoV-2 spike (S) … for
SARS-CoV-2 neutralization, we determined the structures of two human monoclonal antibodies

[PDF][PDF] Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition

AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein… - Cell host & …, 2021 - cell.com
… effects of mutations to SARS-CoV-2, we quantified the ability of each antibody to bind
these … antibodies targeting the core RBD and the RBM (Figure 5D). Three of four antibodies

Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
… Moreover, S309 can broadly neutralize sarbecoviruses, including all currently identified
SARS-CoV-2 VOC, as the epitope sequences recognized by S309 are highly conserved among …

[PDF][PDF] Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies

CO Barnes, AP West, KE Huey-Tubman… - Cell, 2020 - cell.com
… Relatively little is known about antibody recognition of SARSCoV-2 S compared with other
coronavirus S proteins (Graham et al., 2013; Gralinski and Baric, 2015; Wan et al., 2020). How…

[HTML][HTML] Structural basis of receptor recognition by SARS-CoV-2

J Shang, G Ye, K Shi, Y Wan, C Luo, H Aihara, Q Geng… - Nature, 2020 - nature.com
… First, neutralizing monoclonal antibodies that target the SARS-CoV-2 RBM can prevent the
virus from binding to ACE2, and are therefore promising antiviral drugs. Our structure has laid …

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes

WN Voss, YJ Hou, NV Johnson, G Delidakis, JE Kim… - Science, 2021 - science.org
… ” antibodies revealed an NTD epitope that is recurrently mutated among emerging SARS-CoV-2 …
and other non-RBD plasma antibodies are prevalent and have implications for SARS-…

[PDF][PDF] Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

N Suryadevara, S Shrihari, P Gilchuk, LA VanBlargan… - Cell, 2021 - cell.com
… NTDreactive antibodies from a panel of 389 human SARS-CoV-2 … recognizing the NTD.
Three of the 43 NTD-reactive mAbs exhibited neutralizing capacity against authentic SARS-CoV-…