Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection

A Zhang, HD Stacey, MR D'Agostino, Y Tugg… - Nature Reviews …, 2023 - nature.com
… to Omicron full-length spike protein was preserved, suggesting the maintenance of conserved
spike epitopes recognized by non-neutralizing antibodies capable of FcR activation 107 . …

Immunogenicity and crossreactivity of antibodies to the nucleocapsid protein of SARS-CoV-2: utility and limitations in seroprevalence and immunity studies

C Dobaño, R Santano, A Jiménez, M Vidal, J Chi… - Translational …, 2021 - Elsevier
Antibodies to SARS-CoV-2 N were higher in patients with more … of SARS-CoV-2-specific and
HCoV crossreactive antibodies, … of SARS-CoV-2 is immunogenic but it is also recognized by …

Anti-SARS-CoV-2 antibodies within IVIg preparations: cross-reactivities with seasonal coronaviruses, natural autoimmunity, and therapeutic implications

MC Dalakas, K Bitzogli, H Alexopoulos - Frontiers in immunology, 2021 - frontiersin.org
… , antibodies cross-reacting to SARS-CoV-… antibodies recognizing SARS-CoV-2 in uninfected
individuals have conserved epitopes in the spike region targeted by neutralizing antibodies (…

Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies

Y Wang, C Liu, C Zhang, Y Wang, Q Hong, S Xu… - Nature …, 2022 - nature.com
… The SARS-CoV-2 Delta variant is currently the dominant … as a cross-variant broadly neutralizing
antibody and reveal that 8D3 … on the pathogenicity and antibody neutralization of Delta. …

[HTML][HTML] Monoclonal antibody targeting the conserved region of the SARS-CoV-2 spike protein to overcome viral variants

WL Wu, CY Chiang, SC Lai, CY Yu, YL Huang… - JCI insight, 2022 - ncbi.nlm.nih.gov
… We identified mAbs that recognized the S2 region of the … SARS-CoV-2 infection and protect
animals from SARS-CoV-2 … animals from SARS-CoV-2 challenge and neutralized SARS-CoV-…

Structural and antigenic variations in the spike protein of emerging SARS-CoV-2 variants

A Mittal, A Khattri, V Verma - PLoS Pathogens, 2022 - journals.plos.org
… (nAbs) as it plays critical roles in host cell recognition, fusion, and virus entry. The … SARS-CoV-2
variants; (2) the structural basis for antibody-mediated neutralization of SARS-CoV-2 and …

Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits

S Ravichandran, EM Coyle, L Klenow, J Tang… - Science translational …, 2020 - science.org
… (F) Elucidation of the antibody epitope profile in SARS-CoV-2 spike after rabbit vaccination.
Antigenic sites within the SARS-CoV-2 spike protein recognized by serum antibodies after …

SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants

F Tea, A Ospina Stella, A Aggarwal… - PLoS …, 2021 - journals.plos.org
… –cell fusion inhibition compared to those who recognized D614G Spike (Fig 5B), suggesting
antibody recognition. Furthermore, patients who bound D614G Spike had broad SARS-CoV-…

Autoimmune effect of antibodies against the SARS-CoV-2 nucleoprotein

D Matyushkina, V Shokina, P Tikhonova, V Manuvera… - Viruses, 2022 - mdpi.com
… scans: variations; Figure S8: Examples of Western blot with antibody recognition of human
proteins of two cell lines: A549 and T84; Table S1: Comparative data of ELISA to RBD …

[HTML][HTML] N-terminal domain mutations of the spike protein are structurally implicated in epitope recognition in emerging SARS-CoV-2 strains

A Klinakis, Z Cournia, T Rampias - Computational and Structural …, 2021 - Elsevier
… -β15 loops could possibly alter NTD antibody recognition, we analyzed the GISAID mutation
data in order to study the sequence variation profile of SARS-CoV-2 divergent loops. Our …