… However, as with other RNA viruses, such as influenza and HIV (83), further antigenic
drift is anticipated in SARS-CoV-2. Within-host antigenic drift has also been observed in an …

… antigenic drift and, thus, antigenic mismatch between the vaccine strain and the emerging
epidemic strain. SARS-CoV-… used for antigenic characterization of influenza and SARS-CoV-2 …

… S2 domain of SARS-CoV-2 spike can undergo antigenic drift, … for the development of more
universal coronavirus vaccines. … SARS-CoV-2 (1), our results also suggest that antigenic drift …

… question is when and how to update SARS-CoV-2 vaccines to antigenically match … antigenic
drift necessitates periodic vaccine updates. Here, we studied SARS-CoV-2 antigenic drift by …

… recognition of antigenic sites outside the … antigenic shift in SARS-CoV-2. Broadly neutralizing
monoclonal antibodies that recognize RBD epitopes that are conserved among SARS-CoV-…

… Whether such step changes in SARS-CoV-2 biology continue or its evolution becomes …
of antigenic escape and potentially antigenic shift on top of high transmissibility, as shown by …

… and complex recombination, antigenic drift and convergent evolution have enabled SARS-CoV-2
to … We also discuss the potential evolutionary trajectories of SARS-CoV-2 in the future. …

Here, we report the molecular engineering of nanobodies that bind with picomolar affinity to
both SARS-CoV-1 and SARS-CoV-2 receptor-binding domains (RBD) and are highly …

… Rapid genome sequencing of SARS-CoV-2 during the current pandemic revealed antigenic
drift … This antigenic drift resulted in better survival of the virus because of natural selection, as …

… question is when and how to update SARS-CoV-2 vaccines to antigenically match … antigenic
drift necessitates periodic vaccine updates. Here, we studied SARS-CoV-2 antigenic drift by …