… ), S2 domain, and stalk domain of S protein conformations at various pH values. Several key
… conformation. This study will assist in developing novel therapeutic measures against SARS…

… through multiple conformational steps starting from the crystal structures of SARS-CoV-2-…
This results in a comprehensive overview of rigidity and the possible flexible motion trajectories …

… SARS. The enzyme has been shown by X-ray crystallography to undergo significant pH-dependent
conformational changes. Here, we assess the conformational flexibility of the M pro …

… an unusual recognition flexibility type of binding involving five different conformations. TAU-…
exceptional conformational flexibility. According to the fitted structure of each conformation, …

… Cryo-electron microscopy (cryo-EM) allowed to solve the structure of the spike protein of
SARS-CoV-2 confirming that its prefusion conformation has the same overall trimeric structure …

… , the flexibility and conformational dynamics of the SARS-CoV-… not well defined, stable spike
conformations, but virtually a … maximal variance were modeled by flexible fitting. The results …

… This flexibility translates into an ensemble of ACE2 homodimer conformations that could …
of the host receptor toward the large spike conformational changes required for cell fusion. This …

Full article: A higher flexibility at the SARS-CoV-2 main protease active site compared to
SARS-CoV and its potentialities for new inhibitor virtual screening targeting multi-conformers …

… In conclusion, the molecular flexibility as well as conformations of N CoV2 plays a critical
role in drug-binding, RNA-binding and formation of the droplets. Knowledge of the structure …

… severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) … In 2003 the SARS coronavirus
(SARS-CoV) pandemic caused … In our analyses, flexibility properties and conformational …