Convalescent plasma: therapeutic hope or hopeless strategy in the SARS-CoV-2 pandemic

HC Sullivan, JD Roback - Transfusion medicine reviews, 2020 - Elsevier
… Could plasma collected from COVID-19 convalescent patients be efficacious in treating
patients still battling the infection, or as a prophylactic approach to prevent this disease? In this …

Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

QX Long, XJ Tang, QL Shi, Q Li, HJ Deng, J Yuan… - Nature medicine, 2020 - nature.com
… Our group has successfully identified seven patients with SARS-CoV-2 infection from 148 …
antibody titers in eight convalescent patients with COVID-19, four patients showed decreased …

The use of convalescent plasma for pediatric patients with SARS-CoV-2: A systematic literature review

M Zaffanello, G Piacentini, L Nosetti… - … and Apheresis Science, 2021 - Elsevier
… syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019
(… ongoing clinical trials on convalescent plasma therapy in pediatric patients with COVID-19. …

Persistent shedding of viable SARS-CoV in urine and stool of SARS patients during the convalescent phase

D Xu, Z Zhang, L Jin, F Chu, Y Mao, H Wang… - European Journal of …, 2005 - Springer
… viable SARS-CoV from the urine of a convalescent patient has not been reported previously.
Our isolation of living SARS-CoV from the stool specimens of convalescent SARS patients

Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

A Gharbharan, CCE Jordans… - Nature …, 2021 - nature.com
Convalescent plasma is safe, does not improve survival, has … the respiratory tract, influence
SARS-CoV-2 antibody development … of patients already had potent neutralizing SARS-CoV-2 …

SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19

J Wu, B Liang, C Chen, H Wang, Y Fang… - Nature …, 2021 - nature.com
Long-term antibody responses and neutralizing activities in response to SARS-CoV-2
infection are not yet clear. Here we quantify immunoglobulin M (IgM) and G (IgG) antibodies …

Convalescent plasma therapy against the emerging SARS-CoV-2 variants: delineation of the potentialities and risks

M Dhawan, M Parmar, S Angural… - International Journal of …, 2022 - journals.lww.com
… Management with convalescent plasma for treating the SARS patients resulted in reduced
hospital stay and decreased mortality. Following the administration of this plasma, no acute …

SARS-CoV-2 antibody avidity responses in COVID-19 patients and convalescent plasma donors

SE Benner, EU Patel, O Laeyendecker… - The Journal of …, 2020 - academic.oup.com
… optimal convalescent plasma donors. The aim of this study was to characterize SARS-CoV-2 …
and convalescent patients, and compare their association with neutralizing antibody titers. …

Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail

J Hansen, A Baum, KE Pascal, V Russo, S Giordano… - Science, 2020 - science.org
… parallel efforts using both humanized mice and convalescent patients to generate antibodies
against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, …

[HTML][HTML] Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals

L Ni, F Ye, ML Cheng, Y Feng, YQ Deng, H Zhao… - Immunity, 2020 - cell.com
… They also reported that sera from several patients could inhibit SARS-CoV-2 entry in target
cells, indicating involvement of humoral immunity. Krammer and colleagues detected anti-S …