Convalescent plasma: therapeutic hope or hopeless strategy in the SARS-CoV-2 pandemic

HC Sullivan, JD Roback - Transfusion medicine reviews, 2020 - Elsevier
… the use of convalescent plasma in the battle against this new strain of coronavirus, it is …
Accordingly, the aim of this review is to examine in detail studies of convalescent plasma used …

Convalescent plasma as a potential therapy for COVID-19

L Chen, J Xiong, L Bao, Y Shi - The Lancet infectious diseases, 2020 - thelancet.com
… a target and a potential therapeutic against SARS coronavirus 2 (SARS-CoV-2; the causative
… We suggested that this drug could be of use in countering SARS-CoV-2 infections, subject …

The use of convalescent plasma for pediatric patients with SARS-CoV-2: A systematic literature review

M Zaffanello, G Piacentini, L Nosetti… - … and Apheresis Science, 2021 - Elsevier
convalescent plasma therapy for COVID-19 in children. We found insufficient clinical
information on the safety and efficacy of convalescent plasma … that convalescent plasma therapy …

Convalescent plasma therapy against the emerging SARS-CoV-2 variants: delineation of the potentialities and risks

M Dhawan, M Parmar, S Angural… - International Journal of …, 2022 - journals.lww.com
… of convalescent plasma (CP) with higher anti-SARS-CoV-2 IgG … received a transfusion of
convalescent plasma with lower … , patients treated with convalescent plasma vs. conventional …

[HTML][HTML] Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

A Gharbharan, CCE Jordans… - Nature …, 2021 - nature.com
… with 300mL convalescent plasma containing high titers of neutralizing SARS-CoV-2 …
Convalescent plasma is safe, does not improve survival, has no effect on the disease course…

[HTML][HTML] Escape of SARS-CoV-2 501Y. V2 from neutralization by convalescent plasma

S Cele, I Gazy, L Jackson, SH Hwa, H Tegally, G Lustig… - Nature, 2021 - nature.com
… Although we tested only one plasma sample from an individual infected with a SARS-CoV-2 …
a, We obtained convalescent plasma and sequenced the matching infecting virus from …

[HTML][HTML] Convalescent plasma treatment for SARS-CoV-2 infection: analysis of the first 436 donors in England, 22 April to 12 May 2020

H Harvala, J Mehew, ML Robb, S Ijaz, S Dicks… - …, 2020 - eurosurveillance.org
… was primarily collected from individuals for whom SARS-CoV-2 infection had … 256 convalescent
plasma donors were identified as having had a previous laboratory-confirmed SARS-CoV

Dynamics of antibodies to SARSCoV‐2 in convalescent plasma donors

M Steenhuis, G van Mierlo, NIL Derksen… - Clinical & …, 2021 - Wiley Online Library
… Characterisation of the human antibody response to SARS-CoV-2 infection is vital for … with
convalescent plasma or immunoglobulin products derived from convalescent plasma. In this …

[HTML][HTML] SARS-CoV-2 variants and convalescent plasma: reality, fallacies, and opportunities

A Casadevall, JP Henderson… - The Journal of …, 2021 - Am Soc Clin Investig
coronavirus 2 (SARS-CoV-2) isolates identified viral variants that are less susceptible …
neutralization by convalescent plasma (CP), vaccine-elicited plasma/sera, or SARS- CoV-2 …

[HTML][HTML] Antibodies from convalescent plasma promote SARS-CoV-2 clearance in individuals with and without endogenous antibody response

M Marconato, IA Abela, A Hauser… - The Journal of …, 2022 - Am Soc Clin Investig
convalescent plasma studies did not assess neutralizing activity in convalescent plasma
but … any of the antibody types among the 12 SARS-CoV-2 reactivities detected by ABCORA …