… Cytokine storm occurs when both the innate and adaptive human immunity systems are
triggered by SARS-CoV-2. A sudden surge of pro-inflammatory cytokines overwhelms the …

… cytokine storm occurs through the upregulation of cytokine expression via NF-κB. After this
scenario is established, the cytokine storm … stress induces the cytokine storm. This cycle …

… However, it has been previously reported that severe infections caused by SARS coronavirus
may be associated with low levels of IFN production. Therefore, this pathobiologic scenario …

… SARS, MERS and now SARSCoV-2 induce a dysregulated chemokine response commonly
termed as a “cytokine storm… burst release of proinflammatory cytokines, thereby forming the …

… of cytokine storm so far. This paper summarized the mechanism and potential therapeutic
drugs of cytokine storm … analysis, so as to provide references for the treatment of SARS-CoV-2. …

… SARS-CoV, MERS-CoV and SARS-CoV-2 show a relatively higher mortality rates then other
coronaviruses and are all associated with a cytokine storm… , targeting the coronavirus alone …

… cytokine storm driven by PANoptosis and reduce SARS-CoV-2-associated death in mice 92
. Additionally, targeting the pro-inflammatory JAK–STAT signaling pathway in PANoptosis is …

… Thus, it could be suggested that SARS-Cov2 is another possible cause of cytokine storm
syndrome. In conclusion, a deeper knowledge of the pathogenic mechanisms, the genetic …

… Suppressing the cytokine storm is the therapy strategies to prevent the severity and
mortality progression. SARSCoV-2: severe acute respiratory syndrome coronavirus 2; ACE2: …

… We found dramatic increases in circulating cytokines in three of four infected, aged AGMs
but not in infected RMs. All of the AGMs showed increased levels of plasma IL-6 compared …