[HTML][HTML] BNT162b2-induced neutralizing and non-neutralizing antibody functions against SARS-CoV-2 diminish with age

TA Bates, P Lu, YJ Kang, D Schoen, M Thornton… - Cell Reports, 2022 - cell.com
… Each severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant renews
concerns about decreased vaccine neutralization weakening efficacy. However, while prevention …

Neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants induced by natural infection or vaccination: a systematic …

X Chen, Z Chen, AS Azman, R Sun, W Lu… - Clinical Infectious …, 2022 - academic.oup.com
… mutations in spike protein that were associated with decreased neutralizing potency to evade
humoral immunity. However, the decrease in neutralizing potency was more obvious in B.…

[HTML][HTML] SARS-CoV-2 501Y. V2 variants lack higher infectivity but do have immune escape

Q Li, J Nie, J Wu, L Zhang, R Ding, H Wang, Y Zhang… - Cell, 2021 - cell.com
… Moreover, the neutralization resistance we detected for the 501Y.V2 … SARS-CoV-2-susceptible
human cell lines; however, the 501Y.V2 variants were less susceptible to the neutralizing

Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

RE Chen, X Zhang, JB Case, ES Winkler, Y Liu… - Nature medicine, 2021 - nature.com
… 2g), we observed a smaller decrease (2.2-fold, P < 0.01) in neutralization potency of serum
from vaccine recipients against the Wash BR-B.1.1.248 virus (Fig. 4e). Significant differences …

Key mutations in the spike protein of SARSCoV‐2 affecting neutralization resistance and viral internalization

Q Wang, SB Ye, ZJ Zhou, AL Song… - Journal of Medical …, 2023 - Wiley Online Library
… boxes indicate the increase or decrease of the neutralization activity compared with
SARS-… in neutralizing resistance of the SARS-CoV-2 variants, we analyzed the neutralization

Longitudinal dynamics of the neutralizing antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection

K Wang, QX Long, HJ Deng, J Hu… - Clinical Infectious …, 2021 - academic.oup.com
… Little is known about the longitudinal dynamics of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)–specific neutralizing antibodies (NAbs) in patients with COVID-19. …

[HTML][HTML] Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection

ES Winkler, P Gilchuk, J Yu, AL Bailey, RE Chen… - Cell, 2021 - cell.com
… Although passively delivered neutralizing antibodies against SARS-CoV-2 show promise
in … of protection of neutralizing human monoclonal antibodies (mAbs) in SARS-CoV-2-infected …

Neutralization of viruses with European, South African, and United States SARS-CoV-2 variant spike proteins by convalescent sera and BNT162b2 mRNA vaccine …

T Tada, BM Dcosta, M Samanovic-Golden, RS Herati… - BioRxiv, 2021 - biorxiv.org
… The modest decrease in neutralizing titers against viruses with the B.1.1.7, COH.20G/677H
and mink cluster 5 spike proteins by antibodies elicited by BNT162b2 vaccination suggests …

Association between SARS-CoV-2 neutralizing antibodies and commercial serological assays

MS Tang, JB Case, CE Franks, RE Chen… - Clinical …, 2020 - academic.oup.com
SARS-CoV-2 IgG assays and 5 control specimens were analyzed for the presence of neutralizing
antibodies to SARS-CoV-… decreased with an increased threshold for neutralizing titers. …

Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2

J Nie, Q Li, J Wu, C Zhao, H Hao, H Liu… - Emerging microbes & …, 2020 - Taylor & Francis
SARS-CoV-2 pseudovirus, SARS-CoV-2 convalescent patient sera showed high neutralizing
… a robust pseudovirus-based neutralization assay for SARS-CoV-2 and are glad to share …