… Several attempts have been made to design and develop inhibitors against SARS-CoV-2
Mpro. More than 170 crystal structures of the enzyme in complex with the inhibitors and the …

… Structural genomics analysis on spike protein provides important insights to design an
optimized ACE2 for SARS-CoV-2 infection. The structural variations in spike protein (Ser19Pro; …

… be used against the novel coronavirus infection. In this research, we used computational
drug design technologies to repurpose existing drugs as inhibitors of SARS-CoV-2 viral proteins…

… SARS-CoV and SARS-CoV-2, de novo drug design will … insights into both the viral life cycle
and disease progression at an amazing speed. This minireview provides molecular insights …

… SARS-CoV-2 spike protein. We found that species known not to be susceptible to SARS-CoV…
-enhancing mutations that could be used to design ACE2 variants for therapeutic purposes. …

… Design and development of SARS-CoV-2 specific direct-acting … SARS-CoV, MERS-CoV, and
the newly identified SARS-CoV-2 … Potential adaptive mutations in the SARS-CoV-2 genome …

… Based on these run-throughs, we provide insights on the development in combating COVID-…
to the SARS coronavirus and to be 96% homologous to that of a bat-derived coronavirus, …

… The SARS coronavirus was identified as the pathogen of a global outbreak of SARS (severe …
important for revealing their functions and for designing potential anti-SARS therapeutics. …

Dear Editor, The spread of the SARS-CoV-2 variants, especially the global variants of concern
(VOCs), could seriously dampen our efforts to tackle the COVID-19 pandemic. The SARS-…

… interrupt the life cycle of SARS-CoV-2. This structural information presented in this paper
could offer new insights into the follow-up studies of antiviral drug design targeting N protein. …