An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies

Y Liu, WT Soh, J Kishikawa, M Hirose, EE Nakayama… - Cell, 2021 - cell.com
… of RBD and thus enhanced the binding capacity of the spike protein to ACE2 and infectivity
of SARS-CoV-2. Mutational analysis revealed that all of the infectivity-enhancing antibodies …

Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants

Y Cai, J Zhang, T Xiao, CL Lavine, S Rawson, H Peng… - Science, 2021 - science.org
SARS-CoV-2 is an enveloped positive-stranded RNA virus … advanced our knowledge of the
SARS-CoV-2 entry process (… the molecular mechanisms of the enhanced infectivity of B.1.1.…

The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance

I Kimura, Y Kosugi, J Wu, J Zahradnik, D Yamasoba… - Cell reports, 2022 - cell.com
SARS-CoV-2 Lambda, a variant of interest, has spread in some South American countries;
however, its virological features and evolutionary traits remain unclear. In this study, we use …

Infectivity of SARS-CoV-2: there is something more than D614G?

SR Kannan, AN Spratt, TP Quinn, X Heng… - Journal of Neuroimmune …, 2020 - Springer
enhances the infectivity of SARS-CoV-2 virus. However, it is highly unlikely that a seemingly
high infection rate of SARS-CoV-2 is … to the viral replication, infectivity, or a combination of …

Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles

AM Syed, A Ciling, TY Taha, IP Chen… - Proceedings of the …, 2022 - National Acad Sciences
… and a fourth plasmid encoding luciferase mRNA linked to a SARS-CoV-2 packaging signal
(3). … structural gene variants on infectivity, we used the structural genes from SARS-CoV-2 B.1 …

[HTML][HTML] Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron

Z Cui, P Liu, N Wang, L Wang, K Fan, Q Zhu, K Wang… - Cell, 2022 - cell.com
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) … in increased transmissibility,
infectivity, and immune escape as … for enhanced infectivity and immune evasion of SARS-CoV-2 …

Proteolytic activation of SARSCoV‐2 spike protein

M Takeda - Microbiology and immunology, 2022 - Wiley Online Library
… mode of SARS-CoV-2 infection. SARS-CoV-2 variants with enhanced infectivity have been
… , and there is a close relationship between enhanced infectivity and changes in S protein …

[HTML][HTML] SARS-CoV-2 Omicron variant: recent progress and future perspectives

Y Fan, X Li, L Zhang, S Wan, L Zhang… - Signal transduction and …, 2022 - nature.com
… L at the S2 site mediates two distinct SARS-CoV-2 entry pathways. As … enhancing
infectivity. However, the cleavage level of Omicron by furin is the weakest among the SARS-CoV-2 …

Antigenicity and infectivity characterisation of SARS-CoV-2 BA. 2.86

S Yang, Y Yu, F Jian, W Song, A Yisimayi… - The Lancet Infectious …, 2023 - thelancet.com
… 2.86’s RBD are likely to enhance immune evasion as previously reported. 1, 2 Many unusual
… Therefore, an experimental assessment of the antigenicity and infectivity of BA. 2.86 is …

Structural impact of mutation D614G in SARS-CoV-2 spike protein: enhanced infectivity and therapeutic opportunity

A Fernández - ACS medicinal chemistry letters, 2020 - ACS Publications
… , the evolutionary fate of SARS-CoV-2 becomes a matter of … mechanistic clues on the enhanced
infectivity. The D614G … of reducing the infection efficacy of SARS-CoV-2. This therapeutic …