[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape

WT Harvey, AM Carabelli, B Jackson… - Nature Reviews …, 2021 - nature.com
… of mutations. In this Review, we summarize the literature on mutations of the SARS-CoV-2 …
discuss them in the context of observed mutation frequencies in global sequence datasets. …

The global epidemic of SARSCoV‐2 variants and their mutational immune escape

D Tian, YH Sun, JM Zhou, Q Ye - Journal of medical virology, 2022 - Wiley Online Library
… acid mutations and the epidemic characteristics and immune escape of different SARS-CoV-…
new SARS-CoV-2 variants and the development strategy of the second-generation vaccine. …

[HTML][HTML] A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations

C Chakraborty, AR Sharma, M Bhattacharya… - Frontiers in …, 2022 - frontiersin.org
… and partial vaccine escape of the emerging variants with escape mutations. We first …
escape in this direction. Next, we discussed different immune escape strategies of SARS-CoV

SARS-CoV-2 mutations and their viral variants

B Cosar, ZY Karagulleoglu, S Unal, AT Ince… - Cytokine & growth factor …, 2022 - Elsevier
mutations in glycoprotein S lead to vaccine escape is related to the location of the mutation
… In this review, a literature survey in the scope of the increasing SARS-CoV-2 mutations and …

[HTML][HTML] Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies

AJ Greaney, TN Starr, CO Barnes, Y Weisblum… - Nature …, 2021 - nature.com
… Most mutations that escape antibody binding are at sites in the RBD that directly contact the
… To visualize the escape mutations in a structural context, we mapped the extent of escape at …

[HTML][HTML] Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition

AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein… - Cell host & …, 2021 - cell.com
… However, even antibodies targeting the same surface often have distinct escape mutations.
Escape mutants can be selected by passaging virus expressing the SARS-CoV-2 spike …

[HTML][HTML] The global epidemic of the SARS-CoV-2 delta variant, key spike mutations and immune escape

D Tian, Y Sun, J Zhou, Q Ye - Frontiers in immunology, 2021 - frontiersin.org
… key amino acid mutations, the epidemic characteristics, and the immune escape of the Delta
SARS-CoV-2 Delta variant and the development strategy of a second-generation vaccine. …

[HTML][HTML] Human monoclonal antibody combination against SARS coronavirus: synergy and coverage of escape mutants

J Ter Meulen, EN Van Den Brink, LLM Poon… - PLoS …, 2006 - journals.plos.org
… shedding of SARS-CoV in infected ferrets. We generated in vitro SARS-CoV variants escaping
… all had a single P462L mutation in the glycoprotein spike (S) of the escape virus. In vitro …

[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
… In this Review, we provide an overview of observed mutations that are described as impacting
SARS-CoV-2 infectivity and transmissibility, and discuss the viral capacity to escape T cell-…

[HTML][HTML] Generation of SARS-CoV-2 escape mutations by monoclonal antibody therapy

M Ragonnet-Cronin, R Nutalai, J Huo… - Nature …, 2023 - nature.com
… BA.1 escape mutations in patients who received sotrovimab treatment. In addition to mutations
occurring at the P337 and E340 residues, we also identify a novel K356T mutation. These …